DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt-32

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504060.2	Gene:	ugt-32 / 185911	WormBaseID:	WBGene00018543	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	529	Identity:	131/529 - (24%)
Similarity:	214/529 - (40%)	Gaps:	99/529 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLTLPASMQAARILAIFPFPGPSQYINVVPYLKE-LANRGHQVTSVNAFPQKKPVVN------- 65
            :|.::.::..:.|:|...|....| :.|.:..|.: |...||.||...      |:::
Worm     9 ILYSVFSNTDSLRVLVYSPAYAAS-HTNFMARLADTLTEAGHNVTFFT------PIIDESRKDQF 66

  Fly    66 ----FRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKDH 126
                .:||.|.:.....|.      .|:.:  :|:.  |:|.:.........:|..||      |
Worm    67 GVKLTKDVLILEQDEQVKR------NPVTI--DNDM--KYFWTTDVTSANGHKVMGTL------H 115

  Fly   127 FDLI-----------IVEALRSDAY-YGFA-----------AHFNAPIIGISTFGTDWNIDALV- 167
            ...|           :::.|||..| .|.|           .|.....:.::|..|  |.|.|:
Worm   116 KQAIFTCENVFKHQELIDELRSRNYDIGLAEPLMTCGLALFRHIGIEKVMLTTSCT--NYDILLP 178

  Fly   168 --GNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHM---------SEQEKMYAKY 221
              |.....||.|.....:||.|:|.:||.          ||...|:         .::..:|.||
Worm   179 ATGEPEDTSYNPSMNSQVTDVMSFWQRLE----------NYDLYHVMIPTFETIFDDEANVYRKY 233

  Fly   222 ----FPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFI 282
                ||:      ..||..:.||...|....|.||||.:...||:||:.:..:..| |.: |||.
Worm   234 LGESFPD------WRDLIPDASLHFTNSIPFLDFPRPSIQKTIEIGGIAVDIESIP-PVN-EEFS 290

  Fly   283 QGSGEHGV-IYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKL--PGKPSNVFISK 343
            ....:..: :..|.||...|.::|...|:.:|:.|.|.|. ..:||:|.|.:  .....||...|
Worm   291 NILDKRPMNMLISFGSLARSTEMPIIFKENLLRVFQSEPNCTFIWKYESDDVAFANDVENVIFVK 355

  Fly   344 WFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTM 408
            |.||..||...::..|:|||||.||.|:...|||.:..|.|.||..|.....:....:.|..:.:
Worm   356 WMPQTAILKDNRLTAFLTHGGLGSTNEAAFLGKPSVMFPIFADQSRNSNMLGRQEMSIVLHKSDL 420

  Fly   409 TQ-QELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLG 472
            .. |::::....:|...::...||::::..|:||..|.|..:...|:|.|....:||......:.
Worm   421 GNFQKIRDAFHEILHNEKYHLNARKVADMVRNQPAKPRDIFVKHVEFVGRFGPLHHMTPYSLKMP 485

  Fly   473 FFAYHSLDV 481
            |:..:..|:
Worm   486 FYQRYHYDI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	129/512 (25%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	116/467 (25%)
ugt-32	NP_504060.2	Glycosyltransferase_GTB_type	1..508	CDD:299143	131/529 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810