DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt-41

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504818.2	Gene:	ugt-41 / 184295	WormBaseID:	WBGene00017336	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	124/545 - (22%)
Similarity:	211/545 - (38%)	Gaps:	67/545 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLTLPASMQAA-RILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFR----- 67
            |||.|..|..:. ..|.:.|..|.|....:......|...||.||.::.....|    ||
Worm     7 LLLVLSISNTSGFNYLVVSPAFGHSHSTFMGKLADSLTEAGHNVTVLSIIISSK----FRNISYT 67

  Fly    68 ----DVFIPDVFNNYKELINELSGP--MNLW-QENNF---INKFFVSVTRCVLTNKEVTETLLPP 122
                |:.:.:......:|...:...  ...| ||...   |..:.:.:.......|...:..||.
Worm    68 KSTKDIVVVETTTEQDQLTENMENDDFARYWTQEGTMLETIPSYLMFLKMAEDGYKTFRDHALPQ 132

  Fly   123 ------GKDHFDLIIVEALRSDAYYGFA--AHFNAPI-IGISTFGTDWNIDALVGNESPLSYTPL 178
                  .:..:|.:..|   |..:.|.|  .:...|: :.:::...|:....|:|.....||...
Worm   133 MDYLKNNRPQYDAVFFE---SFFFMGKAIQEYLEIPVFLPVTSITHDYRFAELIGEPVSPSYLSG 194

  Fly   179 ATGGLTDRMTFLERLSNFV-----DTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNF 238
            ......:.|.|.|||:|.:     ...:|:.|:             |...:.||.:.:.......
Worm   195 YFTNFGNIMNFQERLTNTISYYLGQILIAFPNW-------------KTLQDPSKDLLVESEYHRA 246

  Fly   239 SLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEF--IQGSGEHGVIYFSLGSNVLS 301
            ..|.:|.:..:.||||.:...||:||:.:..|.....|..|::  |.....|.|: .|.||...|
Worm   247 PYVFINSNPYIDFPRPLLSKTIEIGGITVDVKKLKSEKVDEKWDNILKKRPHNVL-ISFGSMFKS 310

  Fly   302 KDLPADRKDLILKTFASLPQ-RVLWKFEDDK--LPGKPSNVFISKWFPQPDILAHPKVKLFITHG 363
            ..:|...|:.::|...|... ..:||:|.::  ......|:..|||.||..:||..::..|.|||
Worm   311 IYMPDFYKENMVKVMKSFKNVSFIWKYESEETSFANGAENIIFSKWVPQTALLADSRLSAFFTHG 375

  Fly   364 GLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTM-TQQELKETIEILLKEPRFA 427
            ||.|..|..:.|||.|..|.|.||..|.:..|:....:.:....: ....|:..:..:|....::
Worm   376 GLGSVNELSYLGKPALLCPLFADQIRNSKMLTRHNGSIEISKFNLENYNTLRSALHSILFAESYS 440

  Fly   428 QIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQD-----LGFFAYHSLDVIGVLLG 487
            :.|.:::::...||..|.:..:...|:..|..     ....||     :||.||:.||||..|..
Worm   441 ENAEKLAKKLEYQPTKPKELFVRHAEFAARFG-----EQPAQDSNLRTMGFAAYYLLDVIAFLTS 500

  Fly   488 GALLLVAIIVGVLGKLTDFGNAKKK 512
            ..||::.::..::.::......|.|
Worm   501 FVLLVIFVVFIMIRQIVKLLTIKSK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	109/492 (22%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	98/446 (22%)
ugt-41	NP_504818.2	UDPGT	22..510	CDD:278624	117/513 (23%)
ugt-41	NP_504818.2	Glycosyltransferase_GTB_type	26..512	CDD:299143	116/511 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810