Protein Alignment Ugt35B1 and ugt-48

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_504464.2
• Gene: ugt-48 / 178940
• WormBaseID: WBGene00015965
• Length: 526
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 150/560 - (26%)
• Similarity: 247/560 - (44%)
• Gaps: 111/560 - (19%)

  Fly     2 LALRIGFLLLTLPASMQAA---RILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPV 63
            :.|||    ||..|..|..   :||...|....|..|:......||||.||:|  ||..|.   .
 Worm     1 MLLRI----LTFLAVCQVTTSHKILMFSPTASKSHMISQGRIADELANAGHEV--VNFEPD---F 56

  Fly    64 VNFRDVFIP---------DVFNNY--KELINELSGPMNLWQENNFINKFF-----------VSVT 106
            :|..|.|:|         ...|||  |::.|.|||  :::|:::..:|.|           .::.
 Worm    57 LNLTDKFVPCKKCRRWPVTGLNNYKFKKIQNGLSG--DVFQQSSIWSKIFNTDSDPYQDEYTNMC 119

  Fly   107 RCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGFAAHF----NAPIIGIS--------TFGT 159
            ..::||||:.|.|   .|:.|          |||:|...|.    .|.:|||.        |...
 Worm   120 EEMVTNKELIEKL---KKEKF----------DAYFGEQIHLCGMGLAHLIGIKHRFWIASCTMSV 171

  Fly   160 DWNIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEK-------M 217
            ... |:| |..:|.|..|..:........|.:|..|||        .:..|:.::.:       |
 Worm   172 SMR-DSL-GIPTPSSLIPFMSTLDATPAPFWQRAKNFV--------LQMAHIRDEYRDVVLTNDM 226

  Fly   218 YAKYFPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEF- 281
            :.|.|......|:.  |.:...|:.::....|....|.:.|::.:|||.:|.:...|.   |:|
 Worm   227 FKKNFGSDFPCVEF--LAKTSDLIFVSTDELLEIQAPTLSNVVHIGGLGLSSEGGGLD---EKFV 286

  Fly   282 -IQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFED-------DKLPGKP-- 336
             |...|: |||.||||:...:.:||....:.::|        :..||:|       ||...:.
 Worm   287 KIMEKGK-GVILFSLGTIANTTNLPPTIMENLMK--------ITQKFKDYEFIIKVDKFDRRSFD 342

  Fly   337 -----SNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQ 396
                 |||.:..|.||..:||||::|.||||.|..|.:||.:.|.||:.:||.:||..|.|...:
 Worm   343 LAEGLSNVLVVDWVPQTAVLAHPRLKAFITHAGYNSLMESAYAGVPVILIPFMFDQPRNGRSVER 407

  Fly   397 AGFGLGLDHTTMTQ--QELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK 459
            .|:|:..|...:.:  ..::..|:.:|..|.:.:.|.::.:..|.:|.|..:..:..|.:||.:.
 Worm   408 KGWGILRDRFQLIKDPDAIEGAIKEILVNPTYQEKANRLKKLMRSKPQSASERLVKMTNWVLEND 472

  Fly   460 GAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGV 499
            |...::..|:.:.||.:::||:| :......:|:.|::.:
 Worm   473 GVEELQYEGKHMDFFTFYNLDII-ITAASIPVLIFIVLRI 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	89/335 (27%)
ugt-48	NP_504464.2	GT1_Gtf-like	19..451	CDD:340817	128/475 (27%)