DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	135/561 - (24%)
Similarity:	228/561 - (40%)	Gaps:	94/561 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLTLPASMQAARILAIFPFPG------PSQYINVVPYLKELANRGHQVT---------------- 52
            :|.:.:.:....||...|..|      .||..|::      |:.||.||
Worm     9 ILLVISLVSCKNILVYNPIFGYSHAKFVSQLANII------ADHGHNVTVFQPFHIALKNTDGLI 67

  Fly    53 ------SVNAFPQ------KKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSV 105
                  .:|.:|.      ||....|.|.:...:.||  .:::....|..|..|       |...
Worm    68 KNKNIEIINYYPDHYAELLKKKTPTFPDFWDSHLMNN--PVLSSFLMPKALGGE-------FEQT 123

  Fly   106 TRCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNE 170
            |..:..::::...|   ...:||:::.|......:| .|.....|.|.:.:......||:..|..
Worm   124 TTQLFQDQKILNDL---KNRNFDVLLAETFEIAGFY-IADLLEIPSIPLMSAVRLPIIDSAFGQP 184

  Fly   171 SPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYR--FVHMSEQ----------EKMYAKYFP 223
            |.|.|.|.....:.....||:||::.         ||  |.:::.|          :|......|
Worm   185 SILGYFPQQYSKVAPEAGFLDRLNDL---------YRIFFWNLTTQRLCQFQNDFIQKAIGHPVP 240

  Fly   224 EASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHIS----HKPAPLPKDLEEFIQG 284
                  ...||.:...:.:.|.:..|.|..|....::.|||:.|.    ...|.|.::.|..:
Worm   241 ------HWRDLVKESPIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENIL-- 297

  Fly   285 SGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKLPGK---PSNVFISKWF 345
            :.....::.|.||.:.|.::|.:.|..|:|.|.|||. ..:||:|.|.:..:   |.||.:.||.
Worm   298 AERESTVFISFGSVIRSYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNRLPKNVHLKKWV 362

  Fly   346 PQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQ 410
            |||.:||..:||||:|||||.||:|..:.|||.|.:|.|.||..|.....:.|..:..|...:..
Worm   363 PQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHGGAVAYDKFDLAD 427

  Fly   411 -QELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFF 474
             ::|.:|:..::...::...|:::.:....||:.|....:...|:.:..........|....|..
Worm   428 GEKLTKTVRDMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKHRSQVPAINRTGLI 492

  Fly   475 AYHSLDVIGVLLGGA---LLLVAIIVGVLGKLTDFGNAKKK 512
            |::.|||||||...:   |.::..|:.:|.|:......|::
Worm   493 AHYYLDVIGVLTLASIFGLFVIFKILNILRKMISLRKVKRE 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	120/510 (24%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	113/466 (24%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	117/477 (25%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	129/537 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810