DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt-52

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_499988.1	Gene:	ugt-52 / 176904	WormBaseID:	WBGene00018931	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	567	Identity:	124/567 - (21%)
Similarity:	228/567 - (40%)	Gaps:	102/567 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNA------------ 56
            :|....|.|||..:|...:|......|.|........::.|...||.|..:.|
Worm    16 IRCLVFLFTLPRVIQTLHVLFYILLLGKSHIDFTDSLIESLVENGHTVDLIIARMNSHVKSNGTN 80

  Fly    57 FPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLP 121
            ...:|....|::   ...:|....|:|...|....|.|:.:
Worm    81 MVTRKYTYGFQE---ESPWNKAPHLLNPFKGRERTWNEHTY------------------------ 118

  Fly   122 PGKDHFDLI--IVEALRSDAYYGFAAHFNAP--IIGISTFGTD--------WNIDALVGNES-PL 173
                :.|::  :.|...|||  |..|..::.  .|||:|...:        :.|.::|...| |:
Worm   119 ----YMDIVTDLCEIGLSDA--GLHAFISSQKYDIGIATEYENCGVALMKYYKIPSIVSVSSLPI 177

  Fly   174 SYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYR----FVHMS---------EQEKMYAKYFPEA 225
            ........|:.:.....:.:....|.|..|..:|    :.|::         .|.::..|:..|
Worm   178 LDRQSLAAGMPNSPAVTQAIFEAEDLTTYWGKFRNFLNWAHITLIINPYCEKHQSEVIKKHLGE- 241

  Fly   226 SKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFI-QGSGEHG 289
              ....::|..:..|..:|.:..:..||.....:..:||:::......|.:::|:.| |....:|
Worm   242 --NFDTSNLIESLDLAFVNSNELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNG 304

  Fly   290 VIYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFE----DDKLPGKPSNVFISKWFPQPD 349
            ::.|..|:.|.|...|.:.:....:.|...|. ..:||:|    |:::....:|:.:.||.||.|
Worm   305 IVVFCFGTQVPSSLFPIEVRRAFAQAFRHFPDFTFVWKYEMQDGDEQIFANTTNLRLLKWLPQTD 369

  Fly   350 ILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELK 414
            :|...:.|.||:|.||.|.:||.:.|.|:|.:|.|.||..|.......|....||.|.:|...:.
Worm   370 LLNDARTKAFISHVGLNSYLESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIV 434

  Fly   415 ETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLR----HKGAYHMRVAGQDLGFFA 475
            :.:|.:|.:..:...|:::|:...::|..|....:.|.|:..|    |:   ::.:.||::..|.
Worm   435 KGLEAVLYDSSYTLNAKRISKMLHERPNPPKKIFVEWIEFASRNPLLHR---NLNLIGQNMSVFE 496

  Fly   476 YHSLDVIGVLLGGALLLVAIIVGV----------LGKLTDFGNAKKK 512
            |:.||:|..    .:||::|::.|          :|:.. ||..||:
Worm   497 YYCLDIISF----CILLLSIVISVFYLGTGWVSRMGRRV-FGILKKR 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	107/505 (21%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	95/455 (21%)
ugt-52	NP_499988.1	UDPGT	53..537	CDD:278624	113/527 (21%)
ugt-52	NP_499988.1	Glycosyltransferase_GTB_type	<231..517	CDD:299143	75/295 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810