Protein Alignment Ugt35B1 and Ugt2b34

DIOPT Version :9

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_705826.1
• Gene: Ugt2b34 / 100727
• MGIID: 2140962
• Length: 532
• Species: Mus musculus
• Alignment Length: 551
• Identity: 182/551 - (33%)
• Similarity: 277/551 - (50%)
• Gaps: 73/551 - (13%)

  Fly    13 LPASMQAARILAIFPFPG-------------P---SQYINVVPYLKELANRGHQV---------- 51
            :|..|.||.:|.:....|             |   |.::|:...|.||..:||:|
Mouse     1 MPVKMTAALLLLLLQLSGFFGSGTGGKVLVWPMEFSHWLNLKTILDELLKKGHEVMVLRPSASLS 65

  Fly    52 -----TSV---NAFPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLW------QENNFI-NKF 101
                 ||.   ..:|....:....::|    :.:.|:.|.||. ..:.|      ||..:: :|:
Mouse    66 YEVDNTSAIEFETYPTSYSLSELEEIF----WESLKKYIYELP-KQSFWGYFLMLQEMVWVDSKY 125

  Fly   102 FVSVTRCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYG----FAAHFNAPIIGISTFGTDWN 162
            |.|:.:.|:.|||:...|   .|..||:|:     :|.:..    .|.....|::....|.....
Mouse   126 FESLCKDVVFNKELMTKL---QKSRFDVIL-----ADPFIPCGDLLAEVLKIPLVYSLRFFPGST 182

  Fly   163 IDALVGN-ESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEAS 226
            .:...|. ..|.||.|:....|:|||||:||:.|    .:..|.:.|...:..||.:.:.:.|..
Mouse   183 YEKYSGGLPLPPSYVPVVMSELSDRMTFMERVRN----VIYMLCFDFWFQTFNEKNWNQLYTEVL 243

  Fly   227 KR-VQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPA-PLPKDLEEFIQGSGEHG 289
            .| ..|::......:.|:..::.|.||.|.:||...:||||.  :|| ||||::|:|:|.|||||
Mouse   244 GRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFIGGLHC--RPAKPLPKEIEDFVQSSGEHG 306

  Fly   290 VIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHP 354
            |:.|||||.|.|  :..:|.::|....|.:||:|||:||..|.....||..:.||.||.|:|.|.
Mouse   307 VVVFSLGSMVGS--ITEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHS 369

  Fly   355 KVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEI 419
            |.:.||||||.....|:|:||.||:|:|.|.||:.|:......|..:.||..||:..:|...::.
Mouse   370 KTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKAKGAAVRLDFLTMSSTDLHTALKT 434

  Fly   420 LLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGV 484
            :..:|.:.:.|.::|..:.|||:.|||.|::|.|:|:|||||.|:|||..||.:..||||||:|.
Mouse   435 VTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVLGF 499

  Fly   485 LLGGALLLVAII----VGVLGKLTDFGNAKK 511
            ||...|.::.|:    :....|||..|..||
Mouse   500 LLACVLTVMFILKKCCLFCCQKLTKAGRKKK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	160/500 (32%)
		MGT	26..438	CDD:273616	139/459 (30%)
Ugt2b34	NP_705826.1	UDPGT	27..529	CDD:278624	174/522 (33%)
		egt	<272..510	CDD:223071	108/241 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840421
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690