Protein Alignment CG4757 and ces2.4

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001072187.1
• Gene: ces2.4 / 779633
• XenbaseID: XB-GENE-5765838
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 176/600 - (29%)
• Similarity: 269/600 - (44%)
• Gaps: 122/600 - (20%)

  Fly     6 VVELLVLLASS----------SVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLR 60
            ::::|:|..::          .:|:.:....||...||..|.||   .|.|.|:.:|:||:|.||
 Frog     4 LIKVLLLCCATLEIYGTEDARPLLTTKYGQLLGNTVGAKETDRL---VHVFMGVPFAKPPIGPLR 65

  Fly    61 FVNPQPVKPWSPKIFDASEDGPMCPQPWDNM-------------TDVSEDCLRLNVYTKDLKGRR 112
            |..|||.:||| .:.:|:...|||.|....|             ..||||||.|||:|...:|..
 Frog    66 FEAPQPPEPWS-SVREATAAPPMCLQDKRGMEALAKYFKAEFDFPPVSEDCLYLNVFTPADRGEN 129

  Fly   113 ---PVIVFLHPGGF-----YVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGN 169
               ||:||:|.||.     ::|.|.:  |...|     :.|:||:.||||.:||.::|.||..||
 Frog   130 PELPVMVFIHGGGLTMGGAFMFEGTA--LCAYE-----NVVVVSIQYRLGIMGFFSSGDKEVRGN 187

  Fly   170 AGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP 234
            .|..|||.||:|::.:|:.|||:|.|||:.|.|||..||:..:|||:|:||||:.|..|.....|
 Frog   188 FGFLDQVAALQWVRDNIKDFGGNPQSVTIFGESAGGGSVSAQVLSPLSKGLFHKAIAESGVAIIP 252

  Fly   235 --VKYKDND-LQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVV 296
              :..|..: |.:....|.:..|   |:.|:|.|:::|.. |.:.......:|...|.:...:.:
 Frog   253 GFMSSKTEEILPVLSVVANISSC---SVSELVGCLKKKTE-DEIVAITAAMKFVMFPAVVDGVFL 313

  Fly   297 EKDFGQERYLIESPFKTARRGDFHKVALITGIT--EFEFLSGAFFDLRNESIVNRYNRDWEHYAS 359
            .|...:.....||          :.|..:.||.  ||.::....|:|..      |...
 Frog   314 PKPAEEILAAKES----------NPVPFLIGINNHEFGWMLPVAFNLTG------YREG------ 356

  Fly   360 IALLLEQNSTQSRAASRVFREK-------YMPESLDKLEYPKSLK-GMGELLSD------ALIGV 410
                :|:...|:...:.....|       .|.|.....:.||.|: ...:|..|      ||...
 Frog   357 ----MEKKDIQAILGTLPLLNKVPFVIPFIMEEYFGDTDEPKELRNNFLDLAGDTIFVIPALRTA 417

  Fly   411 SFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYL----FHVGLLIPLLKR 471
            .:||     ....|:|.|.|:::.. .|..:.|:  .:...|.|||.::    |...:|:.....
 Frog   418 KYHR-----DSGFPVYFYEFQHRPS-MFADSKDD--FVKADHGDELYFVGGGPFLKSVLLFKSNA 474

  Fly   472 EDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIGNNLTAKS-----G 530
            .:.|..:.:.:.:.|..||:.|||:.      .|| .||.|: :|:.||||  |||.||     |
 Frog   475 TEEEKILSKTIMKYWANFARNGDPNG------LGLAEWPKYD-EDEDYLEI--NLTQKSSQRLKG 530

  Fly   531 GFFLNRYQIWEDLFP 545
            |    |.:.|....|
 Frog   531 G----RLKFWTITLP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	171/569 (30%)
ces2.4	NP_001072187.1	COesterase	25..536	CDD:395084	172/572 (30%)