Protein Alignment CG4757 and Ces2g

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 587
• Identity: 170/587 - (28%)
• Similarity: 272/587 - (46%)
• Gaps: 109/587 - (18%)

  Fly     9 LLVLLA---------SSSVLSIEVDTELGRVRGANL---TSRLGVNFHAFRGIRYAEPPLGDLRF 61
            ||:||.         :|.:.|    |..|:|:|..:   .::.||  |.|.||.:|:||:|.|||
Mouse    17 LLLLLGHVQGHDSPETSPIRS----THSGQVQGRLIHVKDTKAGV--HTFLGIPFAKPPVGPLRF 75

  Fly    62 VNPQPVKPWSPKIFDASEDGPMCPQPWDNMT----------------DVSEDCLRLNVYT---KD 107
            ..|:..:||| .:.|.:....:|||   |:|                .:|||||.||:||   ..
Mouse    76 APPEAPEPWS-GVRDGTSQPAICPQ---NVTMNMEGLKELKLTLPPVSMSEDCLYLNIYTPAHAQ 136

  Fly   108 LKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGL 172
            .....||:|::|.|...|  |.:....|.......|.|:|::.||||.|||.:||.:.|.||.|.
Mouse   137 EGSNLPVMVWIHGGALTV--GMASMYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDEHARGNWGF 199

  Fly   173 KDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP--- 234
            .|||.||||:||:|..|||:||.||:.|.|||.|||:.|::||||:|||||.|..|.....|
Mouse   200 LDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTI 264

  Fly   235 VKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRI---VV 296
            ..:.:...|...:.:|   |.......:|.|:|.|...:.::...           |:::   ||
Mouse   265 FSFSEVVYQTVAKLSG---CEAMDSEALVRCLRGKSEEEILAISK-----------NFQMIPGVV 315

  Fly   297 EKDFGQERYLIESPFKTARRGDFHKVALITGITEFEF------LSGAFFDLRNESIVNRYNRDWE 355
            :.:|     |.:.|.:.....|||.|..|.|....|:      :.|:...::.   :.|.|
Mouse   316 DGEF-----LPKHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSTQTIKG---ITREN---- 368

  Fly   356 HYASIALLLEQNSTQSR---AASRVFREKYMPESLDKLEYPKSLK-GMGELLSDALIGVSFHRFL 416
                :..:|:..:.|..   ..|.:..|:||    :.:|.||:|: ...|::.|.:..:...:..
Mouse   369 ----LQAVLKDTAPQMMLPPECSDLLMEEYM----EDIEDPKTLQIQFTEMMEDFMFVIPSLQVA 425

  Fly   417 QLMSPHTPIYTYLFRYKGRYTFLKN--PDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMI 479
            .....|.|:|.|.|:::.  :|||:  |.:   :...|.||:.::|........|...:.|..:.
Mouse   426 YFQRSHAPVYFYEFQHQS--SFLKDVRPPH---VNADHGDEVPFVFGSFFWGMKLNLTEEEKLLN 485

  Fly   480 ELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGF-FLNRYQIWEDL 543
            ..:.:.|..||:.|:|::::..|     ||::: .|:.||::  |:....|.| ...:.|.|...
Mouse   486 RRMMKYWANFARHGNPNSESLPY-----WPVFD-HDEQYLQL--NIQPAVGQFQKARKLQFWTKT 542

  Fly   544 FP 545
            .|
Mouse   543 LP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	163/560 (29%)
Ces2g	NP_932116.2	COesterase	33..539	CDD:395084	164/564 (29%)