Protein Alignment CG4757 and Ces2el1

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 166/560 - (29%)
• Similarity: 267/560 - (47%)
• Gaps: 89/560 - (15%)

  Fly    24 DTELGRVRGANL-TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQP 87
            :|..|:|||:.: .....::.|.|.||.:|:||:|.|||..|:..:||| .:.||:....||.|.
  Rat    35 NTHTGQVRGSLVHVKDTDIDVHTFLGIPFAKPPVGPLRFAPPEAPEPWS-GVRDATSHPAMCLQN 98

  Fly    88 WDNM---------------TDVSEDCLRLNVY--TKDLKGRR-PVIVFLHPGGFYVFSGQSKYLA 134
             |||               ..:|||||.||:|  |...:|.. ||:|::|.|...|  |.:....
  Rat    99 -DNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEGSNLPVMVWIHGGALTV--GMASMYD 160

  Fly   135 GPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLL 199
            |.......|.|:|::.||||.|||.:||.:.|.||.|..|||.||||:||:|..|||:|:.||:.
  Rat   161 GSMLAATEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIF 225

  Fly   200 GYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVE 264
            |.|||..||:.|::||||:||||..|..|.....|.....:...:.:..|.|..|.......:::
  Rat   226 GESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLPDLISRSSEMVYRIVANLSGCAAVDSETLMQ 290

  Fly   265 CMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGIT 329
            |:|.|...: :...|.:|:.  .|.     ||:.:|     |.:.|.:.....:||:|..|.||.
  Rat   291 CLRGKSEAE-ILDINKVFKI--IPA-----VVDGEF-----LPKHPQELLASANFHRVPSIIGIN 342

  Fly   330 --EFEFLSGAFFD--LRNESIVNRYNRDWEHYASIALLLEQNSTQSR---AASRVFREKYMPESL 387
              |:.::....||  .:.|.|..:         ::..:|:..:.:..   ....:..|:||.::.
  Rat   343 NDEYGWILPMIFDSAQKIEEITRK---------TLPTVLKSTALKMMLPPECGDLLMEEYMGDTE 398

  Fly   388 DKLEYPKSLKG-MGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKN--PDNQQTIG 449
            |    ||:|:. ..|::.|.:..:...:.......|.|:|.|.|::  |.:|.|:  |.:   :.
  Rat   399 D----PKTLQAQFREMMGDFMFVIPALQVAHFQRSHAPVYFYEFQH--RSSFFKDVKPPH---VK 454

  Fly   450 PVHHDELIYLFHVGLLIPLLK--REDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLY 511
            ..|.||:..:|  |.|:..:|  ..:.|..:...:.:.|..||:.|:|::      :|| :||:.
  Rat   455 ADHGDEVFLVF--GYLVGDIKFPHTEEEELLSRKIMKYWANFARHGNPNS------EGLPHWPVM 511

  Fly   512 NAQDKGYLE------IGNNLTAKSGGFFLNRYQIWEDLFP 545
            :..|: ||:      :|..|.|:       |.:.|....|
  Rat   512 DHDDQ-YLQLDIQPSVGRALKAR-------RLKFWTKTLP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	164/553 (30%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	164/553 (30%)