Protein Alignment CG4757 and Ces2j

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_038953911.1
• Gene: Ces2j / 685645
• RGDID: 1591368
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 170/561 - (30%)
• Similarity: 256/561 - (45%)
• Gaps: 94/561 - (16%)

  Fly    24 DTELGRVRGANL---TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCP 85
            :|..|:|||:.:   .::.|:  |.|.||.:|:||:|.|||..|:..:||| .:.||:....||.
  Rat    55 NTHTGQVRGSFVHVKDTKSGI--HTFLGIPFAKPPVGPLRFAPPEDPEPWS-GVRDATSQPAMCL 116

  Fly    86 QP----WDNMTD-------VSEDCLRLNVYT-----KDLKGRRPVIVFLHPGGFYVFS---GQSK 131
            |.    .:.|.:       :|||||.||:|.     :|  ...||:|::|.||....|   ..:.
  Rat   117 QTAMMNLEGMKETELTKLPMSEDCLYLNIYVPAHAHED--SNLPVMVWIHGGGLVGGSASMNDAS 179

  Fly   132 YLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSV 196
            .||..|     :.|:||:.||||.|||.:||.:.|.||.|..||:.||||:||:|..|||:.|||
  Rat   180 TLAATE-----EIVIVSIQYRLGVLGFFSTGDQHARGNWGYLDQMAALRWVQQNIAYFGGNRDSV 239

  Fly   197 TLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGE 261
            |:.|.|||..||:.|::||||:|||||.|..|.....|....|....:.|..|.|..|.......
  Rat   240 TIFGVSAGGTSVSSHVVSPMSKGLFHRAIMQSGVALLPGLISDTSEVVYKTVANLSGCEASDSEA 304

  Fly   262 MVECMRRKPYLDYVSTYNGMFEF--GWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVAL 324
            ::.|:|.|...: :...|.:|:.  |         ||:     .::|.:.|.:.....|||.|..
  Rat   305 LIRCLRAKSKQE-ILAINQVFKMIPG---------VVD-----GKFLPKHPQELLASKDFHPVPS 354

  Fly   325 ITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASR---VFREKYMPES 386
            |.|:...|...|....|....|:|...|:     ::...|:..:.|......   :..|:||.::
  Rat   355 IIGVNTDECGWGVPTILGLYHIINNITRE-----TLPAALKIAAAQMMLPPECIDLIMEEYMGDT 414

  Fly   387 LDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPV 451
            .|........|   |:|.|.:..:...:.........|:|.|.|::  ..:|:|.      :.|.
  Rat   415 EDAETLQAQFK---EMLGDFIFVIPALQVAHFQRSQAPVYFYEFQH--LLSFIKQ------VRPF 468

  Fly   452 -----HHDELIYLF---HVGLLIPLLKREDPENFMIELLTR----MWIEFAQKGDPHNKNDEYLK 504
                 |.|:.:::|   ..|:...|.:.|       |||.|    .|..||:.|:|   |.|.|.
  Rat   469 YPKADHGDDTVFVFGSYFWGMTFDLTEEE-------ELLKRRVMKYWANFARTGNP---NGEDLP 523

  Fly   505 GLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
              :||:.: .|:.||:: |:..|........|.|.|....|
  Rat   524 --HWPVLD-HDEQYLQL-NSQPAVGRALKARRLQFWTKTLP 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	168/554 (30%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	168/554 (30%)