Protein Alignment CG4757 and Ces5a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 577
• Identity: 169/577 - (29%)
• Similarity: 253/577 - (43%)
• Gaps: 121/577 - (20%)

  Fly    25 TELGRVRG--ANLTSRL-GVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQ 86
            |:||.|:|  |.:..|| .||  .|.||.:|.||||.|||..|||..||. .:.:|:....:|.|
Mouse    39 TKLGWVQGKQATVLGRLEPVN--VFLGIPFAAPPLGPLRFSKPQPPIPWD-NLREATAYPNLCFQ 100

  Fly    87 --PW----DNMTDV-------SEDCLRLNVYT---KDLKGRRPVIVFLHPGGFYVFSGQSKYLAG 135
              .|    .|:..|       |||||.||:|.   .:.....||:|::..|||.  :|.:....|
Mouse   101 NLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFE--TGSASIFDG 163

  Fly   136 PEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLG 200
            ....:..|.::|::.||||..||..|.::.||||....||:.||.|::::|:.|||:|||||:.|
Mouse   164 SALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFG 228

  Fly   201 YSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP-VKYKDN----DLQLAKRQAGLLKCPQESIG 260
            .|||:||::..:|||:|..||||.|..|.....| :|..||    |||:.   |.:..|......
Mouse   229 NSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVV---ANVCDCNVSDSK 290

  Fly   261 EMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALI 325
            .:::|:|.|..|:.:|.......|       .|:|....|.:|      |.:...:.....|..|
Mouse   291 ALLKCLREKSSLELMSLSQKAKSF-------TRVVDGSFFSEE------PLELLSQKTLKIVPSI 342

  Fly   326 TGITEFEFLSGAFFDLR---------NESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREK 381
            .|:...|  .|....:|         |||..........|..:..|.:        .....|..|
Mouse   343 IGVNNQE--CGYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYI--------VTKEYFHGK 397

  Fly   382 YMPESL-DKLEYPKSLKGMGEL--LSDALIGVSFHRFLQLMSPHTPIYTYLFRYK------GRYT 437
            :.|..: |.|     |...|::  :...|:...:||     ....|:|.|.|:::      .|..
Mouse   398 HSPTDIRDTL-----LDLFGDVFFVVPGLVTARYHR-----DSGGPVYFYEFQHRPHCFQNSRPA 452

  Fly   438 FLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRE--------DPENFMIELLTRMWIEFAQKGD 494
            |:|..         |.||:.::|..    |.||.:        :.|..:...:.:.|..||:.||
Mouse   453 FVKAD---------HTDEIRFVFGG----PFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGD 504

  Fly   495 PHNKNDEYLKGLN---WPLYNAQDKGYLEIGNNLTAKSGGFFL--NRYQIWEDLFPL 546
            |:        |.:   ||:|: :::.|||:..|:   |.|..|  .|.:.|.|..||
Mouse   505 PN--------GADLPPWPVYD-ENEQYLELDVNI---STGRRLKDQRVEFWTDTLPL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/569 (29%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	165/569 (29%)