Protein Alignment CG4757 and Bche

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_075231.1
• Gene: Bche / 65036
• RGDID: 619996
• Length: 597
• Species: Rattus norvegicus
• Alignment Length: 612
• Identity: 176/612 - (28%)
• Similarity: 279/612 - (45%)
• Gaps: 138/612 - (22%)

  Fly     3 MLFVVELLVLLASS-SVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQP 66
            :|:::.|.:|...| :...:.:.|:.|||||.::.. ||....||.||.||:||||.|||..|||
  Rat     8 LLWILLLCMLFGKSHTEEDVIITTKTGRVRGLSMPI-LGGTVTAFLGIPYAQPPLGSLRFKKPQP 71

  Fly    67 VKPWSPKIFDASEDGPMCPQ-------------PWDNMTDVSEDCLRLNVYTKDLKGRR-PVIVF 117
            :..| |.:::|::....|.|             .|:..|::|||||.|||:....|.:. .|:|:
  Rat    72 LNKW-PDVYNATKYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVPKPKNATVMVW 135

  Fly   118 LHPGGFY-------VFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLA-TGSKEAPGNAGLKD 174
            ::.|||.       |:.|  |:|...|.     .::||:|||:|:||||| .|:.|||||.||.|
  Rat   136 VYGGGFQTGTSSLPVYDG--KFLTRVER-----VIVVSMNYRVGALGFLAFPGNSEAPGNMGLFD 193

  Fly   175 QVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA---APYG--- 233
            |.|||:|||::|..|||:|.||||.|.|||:.||:||:|.|.|..||.|.|..|.   ||:.
  Rat   194 QQLALQWIQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKH 258

  Fly   234 PVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNP---VLNWRIV 295
            |.:.::..|.|||    .:.|.:|:..|::.|:|.|                 :|   :||.::|
  Rat   259 PEEARNRTLTLAK----FIGCSKENEKEIITCLRSK-----------------DPQEILLNEKLV 302

  Fly   296 VEKD------FG---QERYLIESPFKTARRGDFHKVALITGI-----TEFEFLSGAFFDLRNESI 346
            :..|      ||   ...:|.:.|....:.|......::.|:     |.|.......|...|:|:
  Rat   303 LPSDSIRSINFGPTVDGDFLTDMPHTLLQLGKVKTAQILVGVNKDEGTAFLVYGAPGFSKDNDSL 367

  Fly   347 VNRYNRDWEHYASI-----------ALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMG 400
            :.|  |:::...::           |:|.............|:||.:
  Rat   368 ITR--REFQEGLNMYFPGVSSLGKEAILFYYVDWLGDQTPEVYREAF------------------ 412

  Fly   401 ELLSDALIG--------VSF-HRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDEL 456
                |.:||        :.| .:|.:|     .|..:.:.::.|.:.|..|   :.:|.:|..|:
  Rat   413 ----DDIIGDYNIICPALEFTKKFAEL-----EINAFFYYFEHRSSKLPWP---EWMGVMHGYEI 465

  Fly   457 IYLFHVGLLIPLLKRED---PENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGY 518
            .::|  ||  ||.:|.:   .|......:.:.|..||:.|.|   |........||::.:.::.|
  Rat   466 EFVF--GL--PLERRVNYTRAEEIFSRSIMKTWANFAKYGHP---NGTQGNSTVWPVFTSTEQKY 523

  Fly   519 LEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            |.:....:..:......:.|.|...||
  Rat   524 LTLNTEKSKINSKLRAPQCQFWRLFFP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	170/593 (29%)
		Aes	40..>204	CDD:223730	81/185 (44%)
Bche	NP_075231.1	COesterase	21..545	CDD:278561	170/592 (29%)
		Aes	<120..>272	CDD:223730	71/162 (44%)
		AChE_tetra	560..594	CDD:285837

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910