Protein Alignment CG4757 and nlgn3b

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 659
• Identity: 172/659 - (26%)
• Similarity: 262/659 - (39%)
• Gaps: 193/659 - (29%)

  Fly    11 VLLASSSVLSIEVDTELGRVRG---ANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSP 72
            |.:||:......|:|.|||:||   |..|..|| ....:.|:.||.||:|:.||:.|.....||
Zfish    36 VSVASTLTYQPTVNTALGRLRGMRVAVATEGLG-PVDQYLGVPYAAPPVGEKRFMPPDAPSAWS- 98

  Fly    73 KIFDASEDGPMCPQP------------WD--NMTDV-------SEDCLRLNVYTKDLKGR----- 111
            .:.:|:...|:|||.            |.  ||..|       |||||.:|:|.....|.
Zfish    99 GVRNATRFPPVCPQTVRNAVPDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGD 163

  Fly   112 --------------------RPVIVFLHPGGFYVFSGQSKYLAGPEHFMD-------RDCVLVSL 149
                                |||::|:|.|         .|:.|..:.||       .:.::::|
Zfish   164 MSADTERTEDDGLRDSRDDPRPVMLFIHGG---------SYMEGTGNIMDGSVLASYGNVIVITL 219

  Fly   150 NYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLS 214
            |||:|.||||:||.:.|.||.||.||:.|||||.::|..|||||..||:.|...|:..|:|..||
Zfish   220 NYRVGILGFLSTGDQAAKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLS 284

  Fly   215 PMSRGLFHRGICMSAAP-------YGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYL 272
            ..|.|||||.|..|.:.       |.||||    .:|...:.|   |......::|.||:::.|.
Zfish   285 HHSEGLFHRAIIQSGSALSSWSVNYQPVKY----TRLLAERVG---CNVLDTQDLVLCMQKRSYR 342

  Fly   273 DYV--STYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITE---FE 332
            :.|  ......|...:.||::..::.           :.|.....:|:|....::.|:.:   |.
Zfish   343 ELVEQEIQPARFHVAFGPVIDGDLIP-----------DDPEVLMEQGEFLNYDIMLGVNQGEGFR 396

  Fly   333 F-----------LSGAFFDLR------------------NESIVNRYNRDWEHYASIALLLEQNS 368
            |           :||:.||..                  .|:|...|. ||         .::::
Zfish   397 FVEGVVEPEEGGVSGSDFDFTVSDFVDSLYGYPEGKDTLRETIKFMYT-DW---------ADRDN 451

  Fly   369 TQSRAASRVFREKYMPESLDKLEYPKSLKGM---GELLSDALIGVSFH-RFLQLMSPHTPIYTYL 429
            .::|.                    |:|..|   .:.:..|::....| |:      .:|.:.|.
Zfish   452 PETRR--------------------KTLVAMFTDHQWVEPAVVTADLHARY------GSPTFFYA 490

  Fly   430 FRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENF------MIELLTRMWIE 488
            |     |...::|.........|.|||.|:|.|.|:.|  ....|.||      :..::...|..
Zfish   491 F-----YHHCQSPMKPPWADSAHGDELPYVFGVPLIGP--TELFPCNFSRNDIMLSAVVMTYWTN 548

  Fly   489 FAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWED 542
            ||:.|||           |.|.:.: :.:.|..|...|:.||.||.....:. .:...:...|:.
Zfish   549 FAKTGDPNKPVPQDTKFIHTKANRF-EEVTWAKYGPHDQLYLHIGLKPRVRD-HYRATKVAFWKH 611

  Fly   543 LFP-LSSFH 550
            |.| |.:.|
Zfish   612 LVPHLYNLH 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	164/637 (26%)
nlgn3b	XP_005165239.1	COesterase	45..609	CDD:395084	164/637 (26%)
		Herpes_BLLF1	<753..>843	CDD:282904