Protein Alignment CG4757 and ces2a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 582
• Identity: 163/582 - (28%)
• Similarity: 255/582 - (43%)
• Gaps: 120/582 - (20%)

  Fly     3 MLFVVELLVLLASSSVLSIEVDTEL--------GRVRGANLTSR-LGVNFHAFRGIRYAEPPLGD 58
            |:..|.|.:.|..:.|.|..|..:.        |.|||..:.:: .......:.||.:|:||:|.
Zfish     1 MIKDVLLCLCLTLAPVWSAPVQEDSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGP 65

  Fly    59 LRFVNPQPVKPWSPKIFDASEDGPMCPQPWD-------------NMTDVSEDCLRLNVYTKDLKG 110
            .|...||||:.|. .|.:|:|...||.|..|             ....||||||.|||||...:.
Zfish    66 HRLAAPQPVQGWE-GIRNATEHPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRA 129

  Fly   111 ---RRPVIVFLHPGGF-----YVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAP 167
               :.||::::|.||.     .:|.....|...|....:: .|:|.:.||||.||:.:||.:.|.
Zfish   130 ESEKLPVMIWIHGGGLAMGGACMFKELCLYDGTPLAAYEK-VVVVVIQYRLGILGYFSTGDQHAK 193

  Fly   168 GNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPY 232
            ||.|..||:.||:|:||:|:.|||||.|||:.|.|||.||.:|..||||::|||.|.|..|..
Zfish   194 GNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGV-- 256

  Fly   233 GPVK---YKDNDLQLAKRQAGLLKCPQESIGEMVECMRR--KPYLDYVSTYNGMFEFGWNPVLNW 292
            ..||   .||.... |:..|.:.:|...|...:|:|:|.  :..:...:...|:|.
Zfish   257 ATVKGYFVKDPSTH-AQVIANITECDFSSSEVLVKCIREMTEEQIIKAAQKKGIFP--------- 311

  Fly   293 RIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEF---LSGAFFDLRNESIVNRYNRDW 354
            ...|:.:|     :...|.:..:..||.||.::.|.|..||   |...|..           ::|
Zfish   312 GAAVDGEF-----IKAQPEEILKSKDFQKVPILIGTTNHEFGWMLPQIFLP-----------KEW 360

  Fly   355 ----EHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLK-GMGELLSDALIGV---- 410
                :..|:...|...|:..:..|:.:..::|...:    :.|:.:: ...|||.|..:.:
Zfish   361 VKGMDTKAAKDRLGLLNADGASGANGIIADEYFKNA----KTPEEIRDAFTELLGDIFMVIPSIT 421

  Fly   411 --SFHRFLQLMSPHTPIYTYLFRY------KGRYTFLKNPDNQQTIGPVHHDELIYLF------- 460
              |:||     ....|:|.|.|::      |.|.:|:|..         |.|::.::|
Zfish   422 VASYHR-----EAGVPVYMYEFQHGPSTANKFRPSFVKAD---------HADDVGFVFGACFWDV 472

  Fly   461 HVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIG 522
            ||..|..|   .:.||.:...:.:....|.:.|.|:.      ..:.||:|:..:| ||.:|
Zfish   473 HVKGLGTL---TEEENQLCRTVMKYRANFIRTGSPNP------APVPWPVYDQSNK-YLNLG 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	158/565 (28%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	156/558 (28%)