Protein Alignment CG4757 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 658
• Identity: 173/658 - (26%)
• Similarity: 266/658 - (40%)
• Gaps: 196/658 - (29%)

  Fly    23 VDTELGRVRGAN--LTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCP 85
            |:|:.|::|||.  |.|.:......:.|:.||.||:|:.||:.|:|...|| .|.:|:...|:||
Zfish    71 VNTQYGKLRGARVPLHSEILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWS-GIKNATHFAPVCP 134

  Fly    86 QPWDN---------------------MTDVSEDCLRLNVY--TKDLK------------------ 109
            |...|                     :.|.:||||.||:|  |:|:|
Zfish   135 QNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICRKG 199

  Fly   110 -------------------------GRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSL 149
                                     |.:||:|::| ||.|: .|....:.|.......:.::::|
Zfish   200 GTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIH-GGSYM-EGTGNMIDGSVLASYGNVIVITL 262

  Fly   150 NYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLS 214
            |:|:|.||||:||.:.|.||.||.||:.|||||.::|..||||.:.:|:.|...|:..|:|..||
Zfish   263 NFRVGVLGFLSTGDQAAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLS 327

  Fly   215 PMSRGLFHRGICMS-------AAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYL 272
            ..|.|||||.|..|       |..|.||||    .:|...:.|   |......:||:|:|:|
Zfish   328 HHSEGLFHRAIIQSGSALSSWAVNYQPVKY----TRLLAEKVG---CNVLDTLDMVDCLRKK--- 382

  Fly   273 DYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLI------------ESPFKTARRGDFHKVALI 325
                              :.|.:||:|....||.:            :.|.....:|:|....::
Zfish   383 ------------------SARELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIM 429

  Fly   326 TGITEFEFL-------------SGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRV 377
            .|:.:.|.|             ||..||......|:          |:....|...|
Zfish   430 LGVNQGEGLRFVENVVDSEDGVSGNDFDFSVSDFVD----------SLYGYPEGKDT-------- 476

  Fly   378 FRE--KYMPESLDKLEYPKS-LKGMGELLSD------ALIGVSFH-RFLQLMSPHTPIYTYLFRY 432
            .||  |:|.......:.|:: .|.:..|.:|      :::....| |:      .:|.|.|.| |
Zfish   477 LRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY------GSPTYFYAF-Y 534

  Fly   433 KGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRED--PENF------MIELLTRMWIEF 489
            ....:.:|...:.    ..|.||:.|:|.    ||::...|  |.||      :..::...|..|
Zfish   535 HHCQSLMKPAWSD----AAHGDEVPYVFG----IPMIGPTDLFPCNFSKNDIMLSAVVMTYWTNF 591

  Fly   490 AQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDL 543
            |:.|||           |.|.:.: :.:.|..||.||:.||.||.....:. .:...:...|:.|
Zfish   592 AKTGDPNKPVPQDTKFIHTKANRF-EEVAWSKYNPQDQLYLHIGLKPRVRD-HYRATKVAFWKHL 654

  Fly   544 FP-LSSFH 550
            .| |.:.|
Zfish   655 VPHLYNLH 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	168/645 (26%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	168/645 (26%)