Protein Alignment CG4757 and nlgn4xa

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 627
• Identity: 165/627 - (26%)
• Similarity: 260/627 - (41%)
• Gaps: 165/627 - (26%)

  Fly    23 VDTELGRVRGAN--LTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCP 85
            |.|..|::||..  |.:.:......:.||.||.||.|:.||..|:|...| |.|.:|::..|:||
Zfish    45 VTTNYGKLRGLKTPLPNEILGPVEQYLGIPYALPPTGERRFQPPEPPMSW-PGIRNATQFAPVCP 108

  Fly    86 QPWDN----------------------MTDVSEDCLRLNVY---------------------TKD 107
            |..::                      :.|.|||||.||:|                     .||
Zfish   109 QFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNEGGENKD 173

  Fly   108 L---KGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMD-------RDCVLVSLNYRLGSLGFLATG 162
            :   .|.|||:|::|.|         .|:.|..:.:|       .:.::|:||||||.||||:||
Zfish   174 IHDENGLRPVMVYIHGG---------SYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTG 229

  Fly   163 SKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICM 227
            .:.|.||.||.||:.|||||:::||.|.|||..||:.|..||:..|:|..||..|..||.:.|..
Zfish   230 DQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQ 294

  Fly   228 S-------AAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTY--NGMFE 283
            |       |..|.|.||    .::...:.|   |......::|||::.|.|.:.:..|  ...:.
Zfish   295 SGTALSSWAVNYQPAKY----TRILAEKVG---CNMLDSIDLVECLQNKNYKELIEQYITQAKYH 352

  Fly   284 FGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITE---FEFLSGAFFDLRNES 345
            ..:.||::..::.:    ..:.|:|       :|:|....::.|:.:   |:|:.|.   :.:|.
Zfish   353 IAFGPVIDGDVIPD----DPQILME-------QGEFLNYDIMLGVNQGEGFKFVDGI---VDSED 403

  Fly   346 IVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKY-MPESLDKL--------------EYPKS 395
            .|:..:.|:                  |.|......| .||..|.|              |.|::
Zfish   404 GVSANDFDF------------------AVSDFVDHLYGYPEGKDTLRETIKFMYTDWADKENPET 450

  Fly   396 -LKGMGELLSD------ALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHH 453
             .|.:..|.:|      |:.....|  .|..||     ||.:.:   |...::..........|.
Zfish   451 RRKTLVALFTDHQWVAPAVATADLH--AQYGSP-----TYFYAF---YHHCQSEMKPSWSDSAHG 505

  Fly   454 DELIYLFHVGLLIP--LLKREDPEN--FMIELLTRMWIEFAQKGDP-----------HNKNDEYL 503
            ||:.|:|.:.:|.|  |......:|  .:..::...|..||:.|||           |.|.:.:
Zfish   506 DEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF- 569

  Fly   504 KGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            :.:.|..||.:|:.||.||.....:. .:...:...|.:|.|
Zfish   570 EEVAWSKYNPKDQLYLHIGLKPRVRD-HYRATKVAFWLELVP 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	162/620 (26%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:395084	162/620 (26%)