Protein Alignment CG4757 and Ces2h

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001037723.1
• Gene: Ces2h / 498940
• RGDID: 1560889
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 175/595 - (29%)
• Similarity: 260/595 - (43%)
• Gaps: 129/595 - (21%)

  Fly     9 LLVLLASSSVLSIEVDTELGRVRGANLTSR-LGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSP 72
            ||:.:.....||....|..|::.|:.:..: |.|..|:|.||.:|:||:|.|||..|:..:|||
  Rat    19 LLLQVQGQDSLSPIRTTHTGQILGSLIHMKGLDVGVHSFLGIPFAKPPIGPLRFAPPEAPEPWS- 82

  Fly    73 KIFDASEDGPMCPQPWDNMT--------------DVSEDCLRLNVYTKDLK---GRRPVIVFLHP 120
            .:.|.:....||.|....|.              .:|||||.||:||.:..   ...||:|::|
  Rat    83 GVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPLIPMSEDCLYLNIYTPNHAHEGSNLPVMVWIH- 146

  Fly   121 GGFYVFSGQSKY----LAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRW 181
            ||..|....|.|    ||..|     :.|:|::.||||.|||.:||.:.|.||.|..|||.||.|
  Rat   147 GGALVIGMASLYDGSMLAAME-----NVVVVTIQYRLGVLGFFSTGDQHARGNWGYLDQVAALHW 206

  Fly   182 IQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAK 246
            :||:|..|||:||.||:.|.|||..||:.|::|||||||||..|..|...........:...:.:
  Rat   207 VQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSRGLFHGAIMESGVALMSSLISVSSDVVYR 271

  Fly   247 RQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRI---VVEKDFGQERYLIE 308
            ..|.|..|.|.....:|.|:|.|.. :.:.:.|..|          ||   :|:..|     |..
  Rat   272 TVANLSGCEQVDSKALVNCLRGKSE-EEIMSINKAF----------RIISGIVDGIF-----LPR 320

  Fly   309 SPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALL-----LEQNS 368
            .|.:.....|||.:..|.|:...|:                   .|...:|:...     :::..
  Rat   321 HPKELLASADFHPIPSIIGVNNDEY-------------------GWIIPSSMTTTDSKKKMDRQM 366

  Fly   369 TQSRAASRVFREKYMPESLDKL--EYPKSLKGMGELLSDALIGVSFHRFLQ--------LMSPH- 422
            .|:....||.:..:.||..|.|  ||      ||:......:.|.|...::        |...|
  Rat   367 VQAILQKRVAQMMWPPEFSDLLLEEY------MGDSEDPQFLQVQFKEMMEDFTFVIPALQVAHF 425

  Fly   423 ----TPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHV---GLLIPLLKREDPENFMIE 480
                .|:|.|.|::  |.:|.|: .....:...|.||::::|..   |..:.|.:.|       |
  Rat   426 QRSNAPVYFYEFQH--RPSFFKD-SKPPHVKADHGDEILFIFRSFWGGTQVDLTEEE-------E 480

  Fly   481 LLTR----MWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLE------IGNNLTAKSGGFFLN 535
            ||:|    .|..||::|:|:::...|     ||::: .|:.||:      :|..|.||
  Rat   481 LLSRRMMKYWANFARQGNPNSEGLPY-----WPVFD-HDEQYLQLDTQPAVGRALKAK------- 532

  Fly   536 RYQIWEDLFP 545
            |.|.|....|
  Rat   533 RLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	170/577 (29%)
Ces2h	NP_001037723.1	COesterase	30..537	CDD:395084	170/577 (29%)