Protein Alignment CG4757 and LOC4576531

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_315381.5
• Gene: LOC4576531 / 4576531
• VectorBaseID: AGAMI1_014228
• Length: 1170
• Species: Anopheles gambiae
• Alignment Length: 584
• Identity: 184/584 - (31%)
• Similarity: 282/584 - (48%)
• Gaps: 76/584 - (13%)

  Fly     2 LMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQ- 65
            |.|.|......||:::.....|.||.|.:.|    .:.| |::||.||.||:||.|:.||..|:
Mosquito    14 LALAVTLFCGTLAAATEQPPVVHTENGPIVG----EKRG-NYYAFEGIPYAKPPTGERRFAAPEL 73

  Fly    66 PVKPWS-PKIFDASEDGPMCPQ-----PWDNMTDVSEDCLRLNVYTKDLKGRR-----PVIVFLH 119
            ..:.|| |:  :|:..||.|.|     |..:....:||||.:|:||..|.|.:     ..:.::|
Mosquito    74 NDERWSEPR--NATTIGPYCLQWSHTIPGKDKLFGAEDCLYMNIYTTSLDGGQRQTGLSTLFYIH 136

  Fly   120 PGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQ 184
             ||.::|.|..  |..|.|.:.:..::|:.|||||.||||:|.....|||.||||||.||:|:::
Mosquito   137 -GGAFMFGGGG--LFSPNHVLRKPKIMVTFNYRLGPLGFLSTEDDIVPGNFGLKDQVAALQWVRK 198

  Fly   185 HIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQA 249
            :|..|||||:.:||:|:|||..||.||.|||||||||..||..|.....|....::..:.||:.|
Mosquito   199 NIHHFGGDPERITLVGFSAGGASVHLHYLSPMSRGLFQNGIAHSGTALNPWVMAEDSARKAKQIA 263

  Fly   250 GLLKCPQESIGE---MVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQER--YLIES 309
            ..:.||::.:..   ||||:|.:...|.|.....:.::.:||.....:||||.....|  :|.:.
Mosquito   264 RGVGCPEDRLSSSQAMVECLRERTAEDIVRQVPFLLDYLYNPFSPLGVVVEKQSKVNRRPFLADH 328

  Fly   310 PFKTARRGDFHKVALITGITEFEFL-SGAFFDLRNESIVNRYNRDWEHYASIALLLEQNST---- 369
            |...:|:|...||.|:..:|:.|.| .||.| :.|...:...:..|  :..:..:|:..|.
Mosquito   329 PAVLSRKGKLTKVPLVLSVTQGEGLYPGAEF-VSNLDYLADIDARW--HDLLPSILDYKSAVPDD 390

  Fly   370 QSRA-ASRVFREKYMPE----SLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYL 429
            :.|| .|....|.|...    |:|      :.:....:||:.|......:..:|:.||.|:|.|.
Mosquito   391 KRRAELSNAISEHYFGNDRKLSID------NFRDFVSILSNRLFFAGVTKTAKLLQPHIPVYFYY 449

  Fly   430 FRYKGRYTF--LKNPDNQQTIGPVHHDELIYLF-------HVGLLIPLLKREDPENFMIELLTRM 485
            |.||..|..  |.:.......|..|.::::..|       |     ||.|   .|..::.....:
Mosquito   450 FNYKTVYGIGELMSGTEDVNYGVAHGEDVLLSFPTRMRDNH-----PLTK---GELRVVASFVDL 506

  Fly   486 WIEFAQKGDPHNKNDEYLKGLNWPLYNAQDK-GYLEI-----GNNLTAKSGGFFLNRYQIWEDL 543
            :..|:|..:|  |...||    .|:.|...: .|:|:     ....|||: |:.::..|.|:.|
Mosquito   507 YDTFSQGQEP--KYGNYL----LPVQNISGQLRYMEVKDVACDGCATAKT-GYGVSDEQFWDTL 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	177/561 (32%)
LOC4576531	XP_315381.5	None