Protein Alignment CG4757 and LOC4576397

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_001237723.3
• Gene: LOC4576397 / 4576397
• VectorBaseID: AGAMI1_007721
• Length: 597
• Species: Anopheles gambiae
• Alignment Length: 606
• Identity: 188/606 - (31%)
• Similarity: 298/606 - (49%)
• Gaps: 84/606 - (13%)

  Fly     2 LMLFVVELLVLLASS-SVLSI--------------EVDT--------ELGRVRGANLTSRLGVNF 43
            |:|||:..:|...|| |.|.:              ||||        :.|.:.|.......|..|
Mosquito    13 LLLFVMHCVVSCTSSGSPLLVRAALEPNTACASADEVDTGDAPRVCIDDGCLVGTLRDGMGGEQF 77

  Fly    44 HAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDV----SEDCLRLNVY 104
            .||.||.:|:||:|:|||.:|.|..||..::::||.:..||.|..|.:.:.    |||||.||||
Mosquito    78 EAFLGIPFAQPPVGELRFADPLPNGPWFEQLYNASYERDMCLQRNDLLPNPPVTGSEDCLYLNVY 142

  Fly   105 TK---DLKGRRPVIVFLHPGGFYVFSG-QSKYLAGPEHFMD-RDCVLVSLNYRLGSLGFLATGSK 164
            ..   |.:...||||::|.|||  ||| .|..:.|||:.:| :..:||::.||||.||||:||..
Mosquito   143 RPKECDDRTNLPVIVYIHGGGF--FSGTASSLIVGPEYILDTKRAILVTVQYRLGVLGFLSTGDT 205

  Fly   165 EAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA 229
            .||||.|||||.|||||::::|:||||:...:|::|.|||:.||.:||:||:|||||.|.|.||.
Mosquito   206 AAPGNFGLKDQTLALRWVKRNIRRFGGNEQLITIVGQSAGAASVHMHMISPLSRGLFERAIMMSG 270

  Fly   230 APYGPVKYKDND-LQLAKRQA---GLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVL 290
            ....|......| |.||:..|   .::...:.|..::|..:|..|....|...:.:..:..:|:.
Mosquito   271 NSLVPWNIPTKDPLALARSTAMVVDVMGADRLSGKQLVAALRDIPGEKLVGNVHKLKLWSVDPLT 335

  Fly   291 NWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWE 355
            .:|.|||.......:|.|.|..:.|.|::.:|..:.|....|....|....::.::.....|::.
Mosquito   336 LFRPVVEPKDSPNPFLTEEPKVSWRNGNYQQVPYLAGFVPNEGAIRALSIFKDATLFGELQRNFS 400

  Fly   356 HYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYP---KSLKGMGELLSDAL----IGVSFH 413
              ..:.:||||  ..|:|.:...|.:.:.::.|  :.|   .:|:|..:|.|:|.    :.:...
Mosquito   401 --TILPILLEQ--PPSKALTEKMRTRCLNDTTD--DEPVRQDNLQGFVDLYSEAAFIYPVQLGVR 459

  Fly   414 RFLQLM-SPHTPIYTYLFRYKGRYTF--LKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPE 475
            :::... :...|...|...|||||::  :....:....|.||.|:|.|||....:.|......||
Mosquito   460 QYITAADTDRAPASVYKLSYKGRYSYSAIYAGGDTSDYGVVHCDDLNYLFRQPAIFPDYPAGAPE 524

  Fly   476 NFMIELLTRMWIEFAQKG---------DPHNKNDEYLKGLNWPLYNAQD---KGYLEIGNNLTAK 528
            ..|::.....:|:||..|         :..|:|.         :|.:.|   :.::.:|:::..|
Mosquito   525 LKMVDTFVNFFIDFAINGRATPLAPVRECRNENQ---------VYQSLDCDVQEFVRVGDDVQVK 580

  Fly   529 SGGFFLN-----RYQIWEDLF 544
                .||     .:..|:|.:
Mosquito   581 ----VLNARNEEMFAFWKDFY 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	177/581 (30%)
LOC4576397	XP_001237723.3	None