Protein Alignment CG4757 and Ces2h

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 583
• Identity: 174/583 - (29%)
• Similarity: 268/583 - (45%)
• Gaps: 103/583 - (17%)

  Fly     9 LLVLL---ASSSVLSIEVDTELGRVRGANLTSR-LGVNFHAFRGIRYAEPPLGDLRFVNPQPVKP 69
            ||:||   ...|...|.. |..|::.|:.:..: |.|..|:|.||.:|:||:|.|||..|:|.:|
Mouse    17 LLLLLRVQGQDSTSPIRT-THTGQILGSLIHMKDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEP 80

  Fly    70 WSPKIFDASEDGPMCPQPWDNMT--------------DVSEDCLRLNVYTKDLK---GRRPVIVF 117
            |. .:.|.:....||.|....|.              .:|||||.||:|..|..   ...||:|:
Mouse    81 WG-GVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVW 144

  Fly   118 LHPGGFYVFSGQSKY----LAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLA 178
            :| ||..|....|.|    ||..|     :.|:|::.||||.|||.:||.:.|.||.|..|||.|
Mouse   145 IH-GGSLVIGMASMYDGSMLAAME-----NVVVVTIQYRLGVLGFFSTGDERARGNWGYLDQVAA 203

  Fly   179 LRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA--APYGPVKYKDND 241
            |||:||:|..|||:||.||:.|.|||..||:..::||||:||| ||..|.:  |....:....:|
Mouse   204 LRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLF-RGAIMESGVALISSLISVSSD 267

  Fly   242 LQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEF--GWNPVLNWRIVVEKDFGQER 304
            : :.:..|.|..|.|.....:|.|:|.|.. :.:...|..|:.  |         :|:..|
Mouse   268 V-VYQTVANLSGCEQVDSEALVNCLRGKSE-EEIMAINKAFKIIPG---------IVDGIF---- 317

  Fly   305 YLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNST 369
             |...|.:.....|||.|..|.|:...|:  |.........|.::...|.:   .:..:|::.:|
Mouse   318 -LPRHPQELMASADFHPVPSIIGVNNDEY--GWIIPSSMSMIDSKKGMDRQ---MVQAILQRRAT 376

  Fly   370 QSR---AASRVFREKYMPESLDKLEYPKSLK-GMGELLSDALIGVSFHRFLQLMSPHTPIYTYLF 430
            |..   ..|.:..|:||.::.|    |:.|: ...|::.|....:...:..|....|.|::.|.|
Mouse   377 QMMWPPEVSDLLMEEYMGDNED----PQFLQVQFKEMMKDFTFVIPALQVAQFQRSHAPVFFYEF 437

  Fly   431 RYKGRYTFLKNPDNQQTIGPVHHDELIYLFHV---GLLIPLLKREDPENFMIELLTR----MWIE 488
            ::  |.:|.|: .....:...|.||::::|..   |..:...:.|       |||:|    .|..
Mouse   438 QH--RPSFFKD-SKPSHVKADHGDEILFIFRSFWGGTQVDFTEEE-------ELLSRRMMKYWAN 492

  Fly   489 FAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLE------IGNNLTAKSGGFFLNRYQIWEDLFP 545
            ||::.:|:::...|     ||::: ||:.||:      :|..|..:       |.|.|....|
Mouse   493 FARQRNPNSEGLPY-----WPMFD-QDEQYLQLDTQPAVGRALKTR-------RLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	167/562 (30%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:395084	167/563 (30%)