Protein Alignment CG4757 and Nlg4

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 181/715 - (25%)
• Similarity: 277/715 - (38%)
• Gaps: 206/715 - (28%)

  Fly     3 MLFVVELLVL---------LASSSVLSIE---------VDTELGRVRGANL---TSRLGVNFHAF 46
            :|.::.||:|         .|.:|...|.         |.|..||:.|..|   :.|...:...|
  Fly     6 LLLLLRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVF 70

  Fly    47 RGIRYAEPPLGDLRFVNPQPVKPWSP-KIFDASEDGPMCPQPWDN-------------------- 90
            .|:.||.||....||...:...||.. :|.|  :..|:|||...|
  Fly    71 LGVPYATPPTKQNRFSPTRAPAPWDGIRISD--KYSPVCPQRLPNIQNETAALEKMPKGRLEYLK 133

  Fly    91 -----MTDVSEDCLRLNVYTKDLKG----RRPVIVFLHPGGFYVFSG---QSKYLAGPEHFMDRD 143
                 :.:.|||||.|||::....|    :.|||||:|...|...||   ....||.     ..:
  Fly   134 RLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLAS-----YGE 193

  Fly   144 CVLVSLNYRLGSLGFL-ATGSKEA---PGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAG 204
            .|:|:||||||.|||| |..:..|   ..|.||.||:.||.||||:||:|||||:||||.|:..|
  Fly   194 VVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTG 258

  Fly   205 SISVALHMLSP-MSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCP-QESIG----EMV 263
            :..:...|.|| |.||||||.|.||.:.|......::.:..|.:.|..:.|. .:.|.    ::|
  Fly   259 AACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIV 323

  Fly   264 ECMRRKP----YLDYVSTYNGMFEFGWNPVLNWRIV------VEKD----FGQERYLIESPFK-- 312
            :|:|..|    ||..:...|.:..||  |.::..::      ::.|    ....|...:|.|:
  Fly   324 DCLRDVPLEDLYLADIQAPNFLTSFG--PSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSS 386

  Fly   313 ----------------------------------TARRGDFHKV--ALITGITEFEF----LSGA 337
                                              |...|..:.|  .::||.:.:.|    :...
  Fly   387 AGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNG 451

  Fly   338 FFDLRNESIVNRYNR-------------------DWEHYASIALLLEQNSTQSRAASRVFREKYM 383
            |...|.:.|:..|.|                   ||:..:...:     :|:..|.:
  Fly   452 FEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPI-----NTRDTAVA-------- 503

  Fly   384 PESLDKLEYPKSLKGMGELL---------SDALIG-----VSFHRFLQLMSPHTPIYTYLFRYKG 434
              :|...::...:...|::|         |.:..|     .:.........|....|.|:|.|:
  Fly   504 --ALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQ- 565

  Fly   435 RYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLK--REDPENF------MIELLTRMWIEFAQ 491
                .|:.|..|.:|.||.::|.|:|..    ||:.  ...|:|:      :.|.:...|..||:
  Fly   566 ----TKDGDYPQRMGTVHGEDLPYIFGA----PLVDGFSHFPQNYTKSETALSEAVMIFWTNFAR 622

  Fly   492 KGDP--HNKNDEYL---------KGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            .|:|  |::.|..|         :.:.|..|:...:.|||||.....|: .|..::..||..|.|
  Fly   623 TGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKN-HFRAHQLSIWLRLIP 686

  Fly   546  545
              Fly   687  686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	171/682 (25%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	170/671 (25%)