Protein Alignment CG4757 and Nlg1

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 161/603 - (26%)
• Similarity: 242/603 - (40%)
• Gaps: 168/603 - (27%)

  Fly    22 EVDTELGRVRGANLTSRLGV-----NFHAFRGIRYAEPPLGDLRFVNPQPVKPWSP-KIFDASED 80
            |:..:.||:.|  :|.|..|     ....|.|:.|||.|.|:.||:.|....||.. ||  |...
  Fly   157 EIQVKQGRLMG--ITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKI--ARHL 217

  Fly    81 GPMCPQPW--------DNMTDV---------------SEDCLRLNVYT-----KDLKGRRPVIVF 117
            .|:|||..        :||:..               |||||.||:|.     :....:..|:|:
  Fly   218 PPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVY 282

  Fly   118 LHPGGFYVFSGQ-------SKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAP--GNAGLK 173
            ||...|...||.       |.|         .:.::|::|||||.||||.. |.:|.  .|..|.
  Fly   283 LHGESFEWNSGNPYDGSVLSSY---------GEVIVVTVNYRLGVLGFLRP-SIDAHNIANYALL 337

  Fly   174 DQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYK 238
            ||:.||.||:::|:.||||...|||:|:|.|:..|...|:||::.|||||.|.||.:........
  Fly   338 DQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAAS 402

  Fly   239 DNDLQLAKRQAGLLKCP------QESIGEMVECMRRKPYLD--YVSTYNGMFEFGWNPVLNWRIV 295
            :..|||..:.|..|:||      .|....:::|:|.:.|.|  ::.|....|.....|:::..::
  Fly   403 NQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVI 467

  Fly   296 VEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASI 360
            ..:.:....:..|         .|.:..|:.||||.|                      .::...
  Fly   468 PNQPYKVMGHYTE---------HFSRYDLLFGITESE----------------------SYHTLA 501

  Fly   361 ALLLEQN------------STQSR----------AASRVFREKY-MPESLDKLEYPKSLKGMGEL 402
            ||.||:.            ..|||          |..:.:::.| .|.....||:...:.   ::
  Fly   502 ALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVL---DI 563

  Fly   403 LSDA-LIGVSFHRFLQLMSPHTPI----YTYLFRYKGRYTFLKNPDNQQTIGPVHH-------DE 455
            |||| ::|    ..||....|..:    |.|:|.:           |..| ||..|       :|
  Fly   564 LSDARVVG----PLLQTGMFHADVNRRNYMYVFGH-----------NSAT-GPFAHLPHSIMGEE 612

  Fly   456 LIYLFHVGLL----IPLLKREDPENFMIELLTRMWIEFAQKGDPH--------NKN----DEYLK 504
            |.::|...|.    .|.......|..:.|.:...|..|.:.|:|.        |.:    |.|
  Fly   613 LAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRY-- 675

  Fly   505 GLNWPLYNAQDKGYLEIG 522
            .|:||.:|.:.:.||.||
  Fly   676 DLDWPEFNRRAQAYLNIG 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	161/603 (27%)
		Aes	40..>204	CDD:223730	69/206 (33%)
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	161/603 (27%)
		Aes	<263..>408	CDD:223730	54/154 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.810