Protein Alignment CG4757 and Nlg3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 697
• Identity: 163/697 - (23%)
• Similarity: 255/697 - (36%)
• Gaps: 232/697 - (33%)

  Fly    23 VDTELGRVRG--ANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCP 85
            ::|..|.:.|  ..|..|......|:|||.||.||:|:|||:.|.....|| .:..|....|:||
  Fly   158 INTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWS-GVKKADRFSPVCP 221

  Fly    86 Q---------------------------PWDNMTDVSEDCLRLNVY------TKDLKG------- 110
            |                           |:  :.:.|||||.||:|      ::|..|
  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPY--LQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSA 284

  Fly   111 ------------------------------RRPVIVFLHPGGFYVFSGQSKY----LAGPEHFMD 141
                                          :.||:||:| |..|.::..:.|    ||.....:
  Fly   285 GSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVH-GESYEWNSGNPYDGSVLASYGQIL- 347

  Fly   142 RDCVLVSLNYRLGSLGFLATGS---KEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSA 203
                :|::|||||.||||...:   .:.|.|.||.|.:.||.|::::|..|||||:|:||.|:..
  Fly   348 ----VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGT 408

  Fly   204 GSISVALHMLSPMS--RG-LFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQE-SIGEMVE 264
            |:..|.. ::|.|:  .| ||:|.|.||.:...|.....|..:.|...|..:.|..: ....:::
  Fly   409 GAACVHF-LISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMK 472

  Fly   265 CMRRKPYLDY---VSTYNGMFEFGWNPVLNWRIVVEKDF-----GQERYLIESPFKTA------- 314
            |:|.|. ||.   |......|.|.:.|.::..::...|:     |......::...||
  Fly   473 CLREKT-LDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGG 536

  Fly   315 ----------------------RRGDFHKVA---LITGITEFEFLSGAFFD-------------- 340
                                  |:...:|::   |:.|:|..|    |||.
  Fly   537 EAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAE----AFFSFNSGDVQYGIEADR 597

  Fly   341 --------LRN----------ESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESL 387
                    :||          .:|||.|. |||.
  Fly   598 RSRILKAYVRNTYTFHLNEIFATIVNEYT-DWER------------------------------- 630

  Fly   388 DKLEYPKSLKGMG-ELLSDALIGVSFHRFLQLMS-PHTPIYTYLFRYKGRYTFLKNPDNQQTIGP 450
             .:::|.:::... |.||||.:.....:.:.|.| .|...|.|:|.|:.|:     .|..|..|.
  Fly   631 -PVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRF-----GDYPQRQGC 689

  Fly   451 VHHDELIYLFHVGLLIPLL--------KREDPENFMIELLTRMWIEFAQKGDP-------HNKND 500
            :|.::|.|:|..    ||:        .....|..:.|::...|..|.:.|:|       |....
  Fly   690 IHGEDLPYIFGA----PLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQ 750

  Fly   501 E--YLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            |  ..|.:.|..|.:..|.||........|: .:..:|...|.:|.|
  Fly   751 ERSRYKTIEWTAYESVHKKYLNFDTKPKLKN-HYRAHRLSFWLNLIP 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	160/690 (23%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	160/690 (23%)