Protein Alignment CG4757 and alpha-Est3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 168/583 - (28%)
• Similarity: 265/583 - (45%)
• Gaps: 106/583 - (18%)

  Fly    20 SIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDG--P 82
            |::|:|..|.|.|...|...|..:.:|..|.||:||:|.|||:.|.||:|||..: |.::.|  |
  Fly     3 SLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPL-DCTKPGQKP 66

  Fly    83 MCPQPWDNMTDVSEDCLRLNVYTKDLKGRR--PVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCV 145
            :....:....:..||||.||||.|:|...|  |:|||...|||.. ...:|.|..|::||.||.|
  Fly    67 LQFNHYSKQLEGVEDCLYLNVYAKELDSPRPLPLIVFFFGGGFEK-GDPTKELHSPDYFMMRDVV 130

  Fly   146 LVSLNYRLGSLGFLATGSKE--APGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISV 208
            :|:::||:|.||||:.....  .|||||||||:||:.||:::.:||.|||.:||..|.|||:.||
  Fly   131 VVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESAGAASV 195

  Fly   209 ALHMLSPMSRGLFHRGICMSA---APYGPVKYKDNDLQLAKR----------QAGLLKCPQESIG 260
            ...||:|.:.||||:.|..|.   ..:.....|:...:||..          .|.:|...|:..|
  Fly   196 HYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTDAMVLDFLQKLPG 260

  Fly   261 EMVECMRRKPYLDYVSTY--NGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTAR-------- 315
            |.:.    :|||.....:  :.:|:||  |::                  .|:||..
  Fly   261 EKLV----RPYLLSAEEHLDDCVFQFG--PMV------------------EPYKTEHCALPNHPQ 301

  Fly   316 ----RGDFHKVALITGITEFEFLSGAFFDLRNES---IVNRYNRDWEHYASIALLLEQNSTQSRA 373
                :...:::.::...|.||   |.....|.:.   ::....::.||  .:.|.:::|..|:.|
  Fly   302 ELLDKAWGNRIPVLMSGTSFE---GLLMYARVQMAPYLLTSLKKEPEH--MLPLDVKRNLPQALA 361

  Fly   374 ASRVFREKYMPESLDKLEY---------PKSLKGMGELLSDALIGVSFHRFLQLMSPH---TPIY 426
                   :::.:.|.:..:         |:|||...|..|   ..|.:|..|:.:...   :...
  Fly   362 -------RHLGQRLQETHFGGNDPSAMSPESLKAYCEYAS---YKVFWHPILKTLRSRVKSSSAS 416

  Fly   427 TYLFRYKGRYTFLKNPDNQQTI--------GPVHHDELIYLFHVGLLIPLLKREDPENFMIELLT 483
            |||:    |:.|.....|.|.:        |..|.|:..||:: |.....|.:..||...||.:.
  Fly   417 TYLY----RFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWY-GDFSWKLDKHTPEFLTIERMI 476

  Fly   484 RMWIEFAQKGDPHNK--NDEYLKGLNW-PLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDL 543
            .|...||:..:|:.|  .|:..:...| ||.:......|.|..|:...... .|.:.::||.:
  Fly   477 DMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELP-ELQKLRVWESV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	166/578 (29%)
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	166/578 (29%)