Protein Alignment CG4757 and ces2.3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001265277.1
• Gene: ces2.3 / 394897
• XenbaseID: XB-GENE-29209066
• Length: 565
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 181/587 - (30%)
• Similarity: 270/587 - (45%)
• Gaps: 94/587 - (16%)

  Fly     1 MLMLFVVELLVLLASSS--VLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVN 63
            :|:|..|.|.:.....:  :|:.:....||...||..|.||   .|.|.|:.:|:||:|.|||..
 Frog    15 VLLLCCVTLEIYGTEDARPLLTTKYGQLLGNTVGAKETDRL---VHVFMGVPFAKPPIGLLRFEA 76

  Fly    64 PQPVKPWSPKIFDASEDGPMCPQPWDNMTD-------------VSEDCLRLNVYTKDLKGRR--- 112
            |||::||| .:.:|:...|||.|....|.|             ||||||.|||:|...:|..
 Frog    77 PQPLEPWS-SVREATAAPPMCLQDKRGMEDLAEFFKAKFDFPPVSEDCLYLNVFTPADRGENPEL 140

  Fly   113 PVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVL 177
            ||:||:|.||..:  |.:....|.......:.|:||:.||||.:||.::|.||..||.|..|||.
 Frog   141 PVMVFIHGGGLTM--GGASMFEGTALCAYENVVVVSIQYRLGIMGFFSSGDKEVRGNFGFLDQVA 203

  Fly   178 ALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP---VKYKD 239
            ||:|::.:|:.|||:|.|||:.|.|||.:||:..:|||:|:||||:.|..|.....|   ....:
 Frog   204 ALQWVRDNIKDFGGNPQSVTIFGESAGGVSVSAQVLSPLSKGLFHKAIAESGVAILPGLMTSKNE 268

  Fly   240 NDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQER 304
            ..|.|....|.:..|   |:.::|.|:::|.. |.:........|...|.:...:.:.|...:..
 Frog   269 EILPLLSVVANISSC---SVSDLVGCLKKKTE-DEIVAITAAMRFVMFPAVVDGVFLPKPAEEIL 329

  Fly   305 YLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNST 369
            ...||          :.|..:.||...||  |....|.......|...:.:...:|...|....|
 Frog   330 AAKES----------NPVPFLIGINNHEF--GWILPLALNITGYREGMEKKDIQAILGALPLLKT 382

  Fly   370 QSRAASRVFREKYMPESLDKLEYPKSLKG-----MGELL--SDALIGVSFHRFLQLMSPHTPIYT 427
            .|.....:. |:|..::.|    ||.|:.     :|:::  ..||....:||...|     |:|.
 Frog   383 VSNVIPFIM-EEYFGDTND----PKELRNNFLDLVGDIIFVIPALRTAKYHRDSGL-----PVYF 437

  Fly   428 YLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKR--------EDPENFMIELLTR 484
            |.|:::.. .|..:.|:  .:...|.|||.::  ||  .|.||.        .:.|..:.:.:.:
 Frog   438 YEFQHRPS-MFADSKDD--FVKADHGDELYFV--VG--GPFLKSGILFKSNGTEEEKILSKTIMK 495

  Fly   485 MWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIGNNLTAKS-----GGFFLNRYQIWEDL 543
            .|..||:.|||:.      .|| .||.|: :|:.||||  |||.||     ||    |.:.|...
 Frog   496 YWANFARNGDPNG------LGLAEWPKYD-EDEDYLEI--NLTQKSSQRLKGG----RLKFWTIT 547

  Fly   544 FP 545
            .|
 Frog   548 LP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	174/559 (31%)
ces2.3	NP_001265277.1	COesterase	33..544	CDD:395084	175/562 (31%)