Protein Alignment CG4757 and Est-6

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 155/566 - (27%)
• Similarity: 248/566 - (43%)
• Gaps: 107/566 - (18%)

  Fly     3 MLFVVELLVLLASSSVLSIEVDTEL------GRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRF 61
            ::.|:..|.|.:::|    :.|..|      |::||     |...:::::..|.|||||.|||||
  Fly     8 LIIVLSCLWLGSNAS----DTDDPLLVQLPQGKLRG-----RDNGSYYSYESIPYAEPPTGDLRF 63

  Fly    62 VNPQPVK-PWSPKIFDASEDGPMCPQPWDNMTDVS------EDCLRLNVYTKDLKGRR---PVIV 116
            ..|:|.| .|| .||||::....|.| ||..|..:      ||||.::|| |....:|   ||:.
  Fly    64 EAPEPYKQKWS-DIFDATKTPVACLQ-WDQFTPGANKLVGEEDCLTVSVY-KPKNSKRNSFPVVA 125

  Fly   117 FLHPGGFYVFSGQSKYLAGPEHFM-DRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALR 180
            .:| ||.::|.  :.:..|.|:.| :...:||.::||||.|||::||.::.|||.|||||.|||:
  Fly   126 HIH-GGAFMFG--AAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALK 187

  Fly   181 WIQQHIQRFGGDPDSVTLLGYSAGSISVALHML----SPMSRGLFHRGICMSAAPYGPVKYKDND 241
            ||:|:|..|||:|.:|.|:|:|||..||.|.||    ..::|..|              .:..|.
  Fly   188 WIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAF--------------SFSGNA 238

  Fly   242 LQLAKRQAGL----------LKCPQ-ESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIV 295
            |.....|.|.          :.|.. |....:.:|::.||..:.|:.......|.:.|...:..|
  Fly   239 LDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPV 303

  Fly   296 VEKDFGQERYLIESPFKTARRGDFHKVA-LITGITEFEFLSGAFF--DLRNESIVNRYNRDWEHY 357
            :|.....:..:.:.|....:.|.|.:|. .::.:||....:.|..  :.::..:::..|..|...
  Fly   304 LEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLEL 368

  Fly   358 ASIALLLEQNSTQSRA--ASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMS 420
            |...|......|:...  .||..:::|:......:|   |...:..|.:|.|...|....|.|..
  Fly   369 APYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIE---SYSELQRLFTDILFKNSTQESLDLHR 430

  Fly   421 PH--TPIYTYLF---RYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIE 480
            .:  :|.|.|::   ..||....|.|..:.. .|.||.|:...:|              |||:
  Fly   431 KYGKSPAYAYVYDNPAEKGIAQVLANRTDYD-FGTVHGDDYFLIF--------------ENFV-- 478

  Fly   481 LLTRMWIEFAQKGDPHNKNDEYLKGLNW----PLYNAQDKGYLEIG 522
                        .|...:.||.:...|:    ..:.:.|.|.|:.|
  Fly   479 ------------RDVEMRPDEQIISRNFINMLADFASSDNGSLKYG 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	151/549 (28%)
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	149/541 (28%)