DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4757 and Aadacl4fm1

DIOPT Version :10

Sequence 1:NP_650043.1 Gene:CG4757 / 41330 FlyBaseID:FBgn0027584 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_941064.2 Gene:Aadacl4fm1 / 381572 MGIID:2685880 Length:407 Species:Mus musculus


Alignment Length:152 Identity:35/152 - (23%)
Similarity:52/152 - (34%) Gaps:65/152 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   103 VYTKDLK-GRRPV---------------IVFLHPGGFYVFSGQS-----KYLAGPEHFMDRDCVL 146
            |:.|||: |..||               |:|.|.||..:.|..|     .:||     .:.|.||
Mouse    87 VFVKDLRFGTIPVRLFRPKAASSKPRRGILFFHGGGAMIGSLDSHHNLCTFLA-----RETDSVL 146

  Fly   147 VSLNYRL---------------GSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSV 196
            ||:.||.               .|:.||                        :.::.:|.||..|
Mouse   147 VSVGYRKLPYYHHPSLYHDCINASIHFL------------------------KSLKAYGIDPSRV 187

  Fly   197 TLLGYSAGSISVALHMLSPMSR 218
            .:.|.|.|..:..:...:.:||
Mouse   188 VICGESIGGAAAVVVTQTLLSR 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4757NP_650043.1 COesterase 20..540 CDD:395084 35/152 (23%)
Aadacl4fm1NP_941064.2 alpha/beta hydrolases 115..380 CDD:473884 28/124 (23%)
Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3 119..121 1/1 (100%)

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