Protein Alignment CG4757 and gas

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 176/578 - (30%)
• Similarity: 273/578 - (47%)
• Gaps: 94/578 - (16%)

  Fly    22 EVDTELGRVRG-ANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDA--SEDGPM 83
            |:.|:.|:::| ...|...|..:::|.||.:|:||:|:|||..|||...|. .:.|.  :.:.||
  Fly    34 ELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQ-GVRDCTYAREKPM 97

  Fly    84 CPQPWDNMTDVSEDCLRLNVYTKDLKGRR--PVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVL 146
            ......|..:.|||||.||||.|.|:..:  ||:|::..|||.| .|.|:.|.||::||..|.:|
  Fly    98 QRNSITNAAEGSEDCLYLNVYAKRLESPKPLPVMVWIFGGGFQV-GGASRELYGPDYFMKHDILL 161

  Fly   147 VSLNYRLGSLGFLATGSKE--APGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVA 209
            |::|||:|.||||:...||  .|||||||||:.||||::::|..|.|||:|:|:.|.|||..|..
  Fly   162 VTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTH 226

  Fly   210 LHMLSPMSRGLFHRGICMSAAPY-----GPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRK 269
            :.|.:..:||||||.|..|.:..     .|.:.....|......||.|    ||..|::|..::.
  Fly   227 ILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNL----ESEKELLEFFQQI 287

  Fly   270 P------YLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGI 328
            |      |.:.:.|.....::   .:|.:..|:|...|.:..:.:|..:.......:.:.:|.|.
  Fly   288 PASKLAQYCNSIVTQEEQRDY---EILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGG 349

  Fly   329 TEFE-------------FLSGAFFDLRNESIVNRYNR---DWEHYASIALLLEQN--STQSRAAS 375
            |.||             ::..||     |:|:.:..|   |.|..|.:...|:::  ....||:.
  Fly   350 TSFEGLFSYRTTLDDPLYMLSAF-----EAIIPKQVRDAIDKEELAEMVRRLKKSYFDDPDRASM 409

  Fly   376 RVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHR-FLQLMSPHTPIYTYLFRYK------ 433
            .::      |.|..|    |:|....         ..|| .|..::..|.:.|||:|:.
  Fly   410 ELY------ECLHIL----SIKNFWH---------DIHRTLLARLAYATNLPTYLYRFDMDSPHF 455

  Fly   434 GRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNK 498
            ..|..||  ..::..|..|.|::.|:|: |:|...|.:..||...||.|..||..||..|||
  Fly   456 NHYRILK--CGKKVRGVCHADDISYMFY-GILSSKLDKNSPEYRTIERLVGMWTSFATTGDP--- 514

  Fly   499 NDEYLKGLNW-PLYNAQDKGYLEIGNNLTAKSGGFFL-----NRYQIWEDLFPLSSFH 550
            |.|.:..:.| ||.....:..|.|.:.|.      |:     .::.:|:..:...|.:
  Fly   515 NCEIIAPVKWDPLRPGGVENCLNIADGLE------FIPLPESKQFVVWDSFYTRESLY 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	174/566 (31%)
		Aes	40..>204	CDD:223730	79/169 (47%)
gas	NP_611678.1	COesterase	28..534	CDD:278561	170/538 (32%)
		Aes	<117..>222	CDD:223730	54/105 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467392
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.800