Protein Alignment CG4757 and Gli

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 170/639 - (26%)
• Similarity: 254/639 - (39%)
• Gaps: 179/639 - (28%)

  Fly    19 LSIE----VDTELGRVRGANL------------------TSRLGVNFHAFRGIRYAEPPLGDLRF 61
            |::|    |.|..|:|:|..:                  ..|:......|.||.||.||..:.||
  Fly   129 LTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRF 193

  Fly    62 VNPQPVKPWSPKIFDASEDGPMCPQP------WDNMTDVSEDCLRLNVYT----KDLKGRRPVIV 116
            ..|:..:.|  ::..|.:.||.||||      ...:.|:.||||.||||:    ..:..:.||:|
  Fly   194 KPPRVHRGW--QLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMV 256

  Fly   117 FLHPGGFYVFSGQSKYLAGPEHFMDR--DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLAL 179
            ::|.|.|  ..|.|....|  |.:..  |.|:|:||||||:||||:||.:.:|||.|:.||.:||
  Fly   257 YIHGGEF--IRGASNLFQG--HILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMAL 317

  Fly   180 RWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA---APYGPV--KYKD 239
            ||:..:|:.|.||.:|:||.|..||..|..|.|::|.:|.:..|.|..|.   |.:..:  ||:
  Fly   318 RWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYR- 381

  Fly   240 NDLQLAKRQAG-LLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFG------------WNPVLN 291
              .|...|..| ||.|..||..::|.|:|         |....:|.|            |.|||:
  Fly   382 --AQNTSRVLGQLLGCSIESSWKLVNCLR---------TGRSFYELGNAEFSPQVGSFPWGPVLD 435

  Fly   292 -------------WRIVVEKDFGQERYLIESPFKTARRGDFHK-VALITGITEFEFLSGAFFDLR 342
                         ||   |||:   |:|.::|....|.|.|:: :..:||:|..|   .|||..:
  Fly   436 HNFTLPGDDWYEGWR---EKDW---RFLTQTPETLIRAGKFNRNIQYMTGVTTQE---AAFFVAQ 491

  Fly   343 NESIVNRYNRDW--------EHYASIALLLEQNSTQSRAA-----------SRVFREKYMPESLD 388
            |||:...|..|.        ||.......|..|.......           :.:.|::|:
  Fly   492 NESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYI----- 551

  Fly   389 KLEYPKSLKGMGELLSDALIGVSFHRFLQLM-SPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVH 452
                        .:|||........:.::|| ....|:|.|:.              ..|:..::
  Fly   552 ------------NMLSDLYYRAPVDQMVKLMLEQKVPVYMYVL--------------NTTVEALN 590

  Fly   453 --------HDELIYLFHVGLLIPLLKRE--------------DPENFMIELLTRMWIEFAQKGDP 495
                    ||...| |..|  .|.:..|              |.:..|.....:.:..||:.|:|
  Fly   591 LPQWRKYPHDIERY-FLTG--APFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNP 652

  Fly   496 HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQ----IWEDLFP 545
               ..:.:.|:::......:..||.|.   |..:....||..|    .|....|
  Fly   653 ---TPQQVLGMHFQRAYQGEIRYLNIN---TTYNSSILLNYRQTECAFWTQYLP 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	168/632 (27%)
		Aes	40..>204	CDD:223730	70/175 (40%)
Gli	NP_476602.1	COesterase	134..695	CDD:278561	166/627 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440421
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740