Protein Alignment CG4757 and Nlg2

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Alignment Length: 675
• Identity: 174/675 - (25%)
• Similarity: 271/675 - (40%)
• Gaps: 150/675 - (22%)

  Fly     9 LLVLLASSSVL----------SIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVN 63
            |||||..:|:.          |..|.|:.|.:||  :..|......||.||.||.||:|.|||:.
  Fly   161 LLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRG--IVVRSSPLVEAFLGIPYASPPVGSLRFMP 223

  Fly    64 PQPVKPWSPKIFDASEDGPMCPQ---------------PWDNMTDV----------SEDCLRLNV 103
            |.....|. .:..|....|:|||               |...:..:          |||||.||:
  Fly   224 PITPSTWK-TVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNI 287

  Fly   104 Y---------------TKDLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRL 153
            |               |.:.|.:...:||:| |..|.::..:.| .|.|.....:.::|::|:||
  Fly   288 YVPYETRRQRRNTDDTTGEPKTKLSTVVFIH-GESYDWNSGNPY-DGSELAAHGNVIVVTINFRL 350

  Fly   154 GSLGFLATGSKE-APGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMS 217
            |..|||.||.|| |.||.||.|.|..|.|:::::..|||||.|:|||||..|::...:.::||::
  Fly   351 GIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVA 415

  Fly   218 RGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESI-GEMVECMRRKPYLDY--VSTYN 279
            ..|..|.:.:|.:...|...:.|.|.:.:|.|....|..:.: .::..|:|.|...:.  |...:
  Fly   416 SDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDH 480

  Fly   280 GMFEFGWNPVLNWRIVV--EKDFGQERYLIESPFKTA---RRGDFHKVALITGITEFEF------ 333
            ..|..|:.|.::..::.  ....|.....:.|...:.   ...:|.|..||..:|..|.
  Fly   481 PRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSA 545

  Fly   334 --LSGAFFDLRNESIVNRYNRDWEHY--ASIALLLE----------QNSTQSRAASRVF-REKYM 383
              |...|.:.|.:.|:..:.|:..||  ..|..:|:          :|...||.|:..| .:.:.
  Fly   546 QDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHT 610

  Fly   384 PESLDKLEYPKSLKGMGELL----------------SDALIGVSFHRFLQL-MSPHTP------- 424
            ...|.||.|..||:| |...                |.::.|.....:|.| |||..|
  Fly   611 ASPLIKLGYMHSLRG-GRAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQE 674

  Fly   425 --IYTYLFRYKGRYTFLKNPDNQQT---IGPVHHDELIYLFH---------------VGLLIPLL 469
              |...:.||...:....|| ||.|   :.|..::.|....|               ..|.:.:|
  Fly   675 RQIGRLMLRYLSNFAKTGNP-NQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVL 738

  Fly   470 KREDPENFMIELLTRMWIE---------FAQKGDPHNKNDEYLKGLNWPLYNAQD---KGYLEIG 522
            ..:...|.|.|  .|.:|.         |.|.|....::.....|...|.::|.|   :.|:|:|
  Fly   739 YNQRRSNAMHE--KRSYIRRRLRSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELG 801

  Fly   523 N--NLTAKSGGFFLNRYQIWEDLFP 545
            |  |:.:...|   ::..:|.:|.|
  Fly   802 NKANIQSHYRG---HKLSMWLNLIP 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/647 (26%)
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	145/553 (26%)