Protein Alignment CG4757 and Nlg3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 666
• Identity: 171/666 - (25%)
• Similarity: 255/666 - (38%)
• Gaps: 193/666 - (28%)

  Fly     8 ELLVLLASSSVLSIEVDTELGRVRGA--NLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPW 70
            |.|....||.:    |.|:.|.|.|.  :|..|......||||:.||.||:|:|||:.|.....|
Mosquito    55 ETLKKSTSSRI----VHTKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALW 115

  Fly    71 SPKIFDASEDGPMCPQ---------------------------PWDNMTDVSEDCLRLNVYTKDL 108
            | .:..|....|:|||                           |:  :.:.|||||.||:|....
Mosquito   116 S-GVKKADRFSPVCPQRLPDIYNETAALERMPRGRLEYLRRLLPY--LRNQSEDCLYLNIYVPTQ 177

  Fly   109 KGRR--------PVIVFLHPGGFYVFSGQSKY----LAGPEHFMDRDCVLVSLNYRLGSLGFLAT 161
            .|.|        .|:||:| |..|.::..:.|    ||.....:     :|::|||||.||||..
Mosquito   178 AGSRESSSTSKYAVVVFVH-GESYEWNSGNPYDGSVLASYGQIL-----VVTINYRLGILGFLNA 236

  Fly   162 G---SKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHML---SPMSRG- 219
            .   ..:||.|.||.|.:.||.|||::|:.|||||.||||.|:..|:..|  |.|   :.:..|
Mosquito   237 NVDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACV--HFLIASAAVPEGL 299

  Fly   220 LFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKC-PQESIGEMVECMRRKPYLDYVSTYNGMFE 283
            ||||.|.||.:...|........:.|...:..:.| |......:::|:|.||..|.:||.....:
Mosquito   300 LFHRAIMMSGSGLAPWSLVGEPAKFAAYVSHHVNCSPDLPHQLLLKCLRDKPLEDILSTSVRAPD 364

  Fly   284 FG--WNPVLNWRIVVEKDFGQERYL--------IESPFKTARRGDFH------------------ 320
            ||  :.|.::..::   |.|:.:.:        ..:|..|......|
Mosquito   365 FGNAFGPSVDGVVI---DTGEIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINK 426

  Fly   321 --KVALITGITEFEFLSGAFFDLRNE--------------------------------SIVNRYN 351
              |..|:.|:|..|    |:|...:|                                :|||.|.
Mosquito   427 LSKYDLLVGVTRAE----AYFAFNSEDVQYGIEADRRAKILKNYVRSTYSFHLNEILATIVNEYT 487

  Fly   352 RDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMG-ELLSDALIGVSFHRF 415
             |||.                                .:::|.:::... |.||||.|.....:.
Mosquito   488 -DWER--------------------------------PVQHPINIRDETLEALSDARIVAPAVQT 519

  Fly   416 LQLMS-PHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLL--------KR 471
            ..|.| .|...:.|:|.|:.::     .|..|..|.:|.::|.|||..    ||:        ..
Mosquito   520 ADLHSADHRNSFLYVFDYQTKF-----GDFPQRQGCIHGEDLPYLFGA----PLVGGFNHFTRNY 575

  Fly   472 EDPENFMIELLTRMWIEFAQKGDPHN--KNDEY-----LKGLNWPLYNAQDKGYLEIGNNLTAKS 529
            ...|..:.|.:...|..|.:.|:|:.  :||..     .|.:.|..|.:..|.||.:......|:
Mosquito   576 TKSEIALSEAVMIYWSNFIRTGNPNEQLENDHVRDRTRFKNIEWTPYESVHKKYLNLDTKPKLKN 640

  Fly   530 GGFFLNRYQIWEDLFP 545
             .:..:|...|.:|.|
Mosquito   641 -HYRAHRLSFWLNLVP 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	164/647 (25%)
Nlg3	XP_061500330.1	None