Protein Alignment CG4757 and cel.1

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_955901.2
• Gene: cel.1 / 322481
• ZFINID: ZDB-GENE-030131-1201
• Length: 550
• Species: Danio rerio
• Alignment Length: 552
• Identity: 166/552 - (30%)
• Similarity: 249/552 - (45%)
• Gaps: 60/552 - (10%)

  Fly     1 MLMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQ 65
            ||.:|:..:|.|..:.......|.||.|.|:|.:.:..|......|:||.:|.||   .||..|.
Zfish     3 MLGVFISAVLFLGTAQGASLGAVLTEGGMVQGKSRSVGLFRYMDTFKGIPFAAPP---KRFEKPV 64

  Fly    66 PVKPWSPKIFDASEDGPMCPQPWDNMTDV--SEDCLRLNVYT---KDLKGRRPVIVFLHPGGFYV 125
            ....|. .:...::....|.|.....|||  |||||.||::.   :.:....||:||::.|.|.:
Zfish    65 AHPGWE-GVLKTTDYRKRCLQLNLLATDVIGSEDCLYLNIWVPQGRTVSSNLPVMVFIYGGAFLL 128

  Fly   126 FSGQ-----SKYLAGPEHFMDR-DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQ 184
            ..||     ..||...|...|| :.::|:.|||:|:|||::||....|||.||.||..|:.|:.:
Zfish   129 GGGQGANFLDNYLYDGEEMADRGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQHAAISWVHR 193

  Fly   185 HIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQA 249
            :|:.|||:||::||.|.|||:.||...:::|.::|:..|.|..|.....|.....|..|.|:..|
Zfish   194 NIKAFGGNPDNITLFGESAGAASVNFQIITPKNKGMIRRAISQSGVALCPWAISRNPRQFAEEIA 258

  Fly   250 GLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNP----VLNWRI--VVEKDFGQERYLIE 308
            ..:.||.:|  .|.:|::|..  ....|..|..:...:|    |.|..:  |::.||..:.  .|
Zfish   259 TKVGCPIDS--GMADCLKRAD--PKAVTLAGKLKLTSSPDAPIVHNLYLSPVIDGDFIPDE--PE 317

  Fly   309 SPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRY-NRDWEHYASIALLLEQNSTQSR 372
            :.|..|...|:     |.|:.:.:....|..|:  .||.|.. ....|...::|..|.::..|.
Zfish   318 TLFGNAADIDY-----IAGVNDMDAHIFATIDI--PSINNALTTTPVEEVQALATALSRDRGQD- 374

  Fly   373 AASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTP------IYTYLFR 431
            |....|:| |.....||....|..:.:.||.:|.:..|.....|.|   ||.      .::|||.
Zfish   375 AGIATFQE-YTVNWGDKPNKEKVKQTVVELETDYMFLVPTQAALYL---HTDNAKSARTFSYLFT 435

  Fly   432 YKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPL---LKREDPENFMIELLTRMWIEFAQKG 493
            ...|.     |.....:|..|.|||.|:|......||   .:..|...:||    ..|..|||.|
Zfish   436 ESSRI-----PVFPLWMGADHADELQYVFGKPFATPLGYFPRHRDVSKYMI----AYWSNFAQTG 491

  Fly   494 DPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNL 525
            || ||.:..:. :.||.::.....||:|.|.:
Zfish   492 DP-NKGESKVP-VTWPEFSNPGHQYLDINNKM 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	161/538 (30%)
		Aes	40..>204	CDD:223730	64/174 (37%)
cel.1	NP_955901.2	COesterase	25..517	CDD:306613	159/524 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750