Protein Alignment CG4757 and Nceh1

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_848887.1
• Gene: Nceh1 / 320024
• MGIID: 2443191
• Length: 408
• Species: Mus musculus
• Alignment Length: 203
• Identity: 47/203 - (23%)
• Similarity: 78/203 - (38%)
• Gaps: 66/203 - (32%)

  Fly    31 RGA----NLTSRLGVNFHAFRGIRYAEPPLGDLRFV----NPQPVKPWSPKIFDASEDGPMCPQP 87
            |||    ||...||:|.|           |..|.|:    ..|..:. |||:
Mouse    41 RGAQQVSNLIHSLGLNHH-----------LIALNFIITSFGKQSARS-SPKV------------- 80

  Fly    88 WDNMTDVSEDCLRLNVYTKDLKGRRPV---IVFLHPGGFYVFSGQSKYLAGPEHFMDRDC----- 144
              .:||...|.:.:.|:....|...|:   ::::|.||:.:.|.:..|       .|:.|
Mouse    81 --KVTDTDFDGVEVRVFEGSPKPEEPLRRSVIYIHGGGWALASAKISY-------YDQLCTTMAE 136

  Fly   145 ----VLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQH--IQRFGGDPDSVTLLGYSA 203
                |:||:.|||....:..         ..:.|.:.|.::..|.  :.::..||..|.:.|.||
Mouse   137 ELNAVIVSIEYRLVPQVYFP---------EQIHDVIRATKYFLQPEVLDKYKVDPGRVGISGDSA 192

  Fly   204 -GSISVAL 210
             |:::.||
Mouse   193 GGNLAAAL 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	47/203 (23%)
Nceh1	NP_848887.1	Abhydrolase_3	109..381	CDD:400284	25/108 (23%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		1/1 (100%)