Protein Alignment CG4757 and cest-9.2

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 154/570 - (27%)
• Similarity: 245/570 - (42%)
• Gaps: 113/570 - (19%)

  Fly     2 LMLFVVELLVLLASSSVLSIEV-DTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQ 65
            |..|::..|:|| ...:.|::| :|..|||||....|....:.:.|:.:.:|:||:|.|||..||
 Worm     3 LKKFILFKLILL-FPDIQSLKVIETSYGRVRGITEWSDDNNHKYMFKSVPFAKPPIGKLRFAPPQ 66

  Fly    66 PVKPWSPKIFDASEDGPMC---------PQPWDNMTDVSEDCLRLNVYT--KDLKGRRPVIVFLH 119
            ....|| .:.|||:..|.|         ||     ..||||||.:|::|  |.|:.:..|||:.|
 Worm    67 YPDSWS-GVLDASKYSPACLSNSSTTSTPQ-----EHVSEDCLYINIFTSEKCLRSKCAVIVYFH 125

  Fly   120 PGGFYVFSGQSKYLAGPEHFMDR----DCVLVSLNYRLGSLGFLATG-SKEAPGNAGLKDQVLAL 179
             ||.|  :|.|..:......::|    |.:|.....|||..|.|..| |.....|..:.|.|.||
 Worm   126 -GGAY--NGDSATMFPDNFILERYVAEDVILAIPGVRLGVFGQLYFGPSALLTENLFMFDAVQAL 187

  Fly   180 RWIQQHIQRFGGDPDSVTLLGYSAGSISV-AL---HMLSPMSRGLFHRGICMSAAPYGPVKYKD- 239
            .::...|..|||||..||::|:|:|...| ||   :.:.|..: ||.:.|.:|..  |...:.|
 Worm   188 DFVHNEIPNFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDLK-LFQQIIVLSGT--GMFGFYDL 249

  Fly   240 --NDLQLAKRQAGLLKCPQE-----SIGEMVECMRRKPYLDYVSTYNGM---FEFGWNPVLNWRI 294
              ::..:...:.|.....||     :|.|::||||:....:.|.....|   ::..:..:|....
 Worm   250 LVDNSFIISEKLGCFNGTQEERTDANIAEILECMRQIDGHEIVGMQKHMEDVYKLTFKSLLRGAP 314

  Fly   295 VVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYAS 359
            .:|.:...|::...:..:.|          |.|.||:||        |||  |.||     .|.:
 Worm   315 FMELNGKIEKFRNSTSPRNA----------IFGTTEYEF--------RNE--VERY-----LYIT 354

  Fly   360 IALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDAL-IGVSFHRFLQLMSPHT 423
            ...|..:|..   |.::.|.::.| :::|.:           :..||: |.||...|...|: :.
 Worm   355 TTFLDFENPV---AVAQHFDDELM-QNMDTM-----------INGDAVSIFVSAAAFSSAMA-NA 403

  Fly   424 PIYTYLFRYK-GRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWI 487
            ....|||..: ..|:|..: |.|..||  .|.|:::...:.:|         ::|..:||    :
 Worm   404 GADVYLFETRQWPYSFHVS-DMQYFIG--IHREVLHTHDMDIL---------DSFYSKLL----V 452

  Fly   488 EFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRY 537
            .|.:.|.|..:         |.....:...|||:..:.....|...|..|
 Worm   453 NFTKTGAPSPE---------WNSLEPEKMNYLELRVDTRNGKGPVMLEGY 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	149/552 (27%)
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	148/550 (27%)