Protein Alignment CG4757 and Ces1a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 570
• Identity: 170/570 - (29%)
• Similarity: 260/570 - (45%)
• Gaps: 91/570 - (15%)

  Fly     2 LMLFVVELLVL--------LASSSVLSIEVDTELGRVRGANLTSRLGVN-FHAFRGIRYAEPPLG 57
            :.||.:.|..|        |:|..|    |||..|:|.|..::...... ...|.|:.:|:||||
Mouse     1 MWLFALALASLNTCMALGHLSSPPV----VDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLG 61

  Fly    58 DLRFVNPQPVKPWSPKIFDASEDGPMCPQ--------------PWDNM-TDVSEDCLRLNVYT-K 106
            .|||..|||.:.|| .:.:.:...|||.|              ..:|: .:.|||||.||:|: .
Mouse    62 PLRFAPPQPAETWS-SVKNTTSYPPMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPT 125

  Fly   107 DL--KGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGN 169
            ||  |.|.||:|::|.||  :.||.:....|.......:.|:|.:.||||..|||:||.:.:.||
Mouse   126 DLTSKDRLPVMVWVHGGG--LLSGGASTFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSRGN 188

  Fly   170 AGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP 234
            .|..|||.||:|:|.:|..|||||.||||.|.|||..||::.:|||:::.||.|.|..|.....|
Mouse   189 WGHLDQVAALQWVQNNIANFGGDPSSVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTP 253

  Fly   235 VKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWN---------PVL 290
            ..:::...:.|::.|....|...:..::|.|:|.|...:.::|...|..|..:         |.|
Mouse   254 CLFRETTRRAAEQVAIATGCVATTSADIVHCLREKTEEELLATTLKMKFFALDLLGDPRESYPFL 318

  Fly   291 NW---RIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNR 352
            ..   .:|:.|  ..|..|.|..|.|        |..|.||.:.||  |.|..:.....::....
Mouse   319 TTVIDGVVLPK--APEEILAEKSFNT--------VPYIVGINKQEF--GWFIPMMMGYPLSEGKL 371

  Fly   353 DWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMG-ELLSDALIGV------ 410
            |.:...|:.......:..|:..:.|..|||:..|    :.|...|.:. :::.|.|..|
Mouse   372 DQKSATSLLWKSYPLTNISKELTPVATEKYLGGS----DCPDKKKDLFLDMMGDVLFAVPSVIVA 432

  Fly   411 SFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKR--ED 473
            .:||     ....|.|.|.|:|...:.....|   :|:...|.||:..::..    |.||.  .:
Mouse   433 RYHR-----DAGAPTYMYEFKYHPSFVSDMRP---KTVIADHGDEVYSVWGT----PFLKEGASE 485

  Fly   474 PENFMIELLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIG 522
            .|..:..::.:.|..||:.|:|:.      :|| :||.| .:.:.||:||
Mouse   486 EEINLSTMMMKFWGNFARNGNPNG------EGLPHWPEY-GEKESYLQIG 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	163/544 (30%)
Ces1a	NP_001013786.2	COesterase	22..545	CDD:395084	165/549 (30%)