Protein Alignment CG4757 and Ces4a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 595
• Identity: 173/595 - (29%)
• Similarity: 264/595 - (44%)
• Gaps: 111/595 - (18%)

  Fly    12 LLASSSVLSIEVDTELGRVRGAN--LTSRLGV-----------NFHAFRGIRYAEPPLGDLRFVN 63
            :|..|..|.:.|.|.||.:....  |.::.|:           ....|.||.:::||:|..||..
Mouse    11 ILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIQVFLGIPFSKPPVGTRRFAP 75

  Fly    64 PQPVKPWSPKIFDASEDGPMCPQ-PWDNMTDV-------------SEDCLRLNVYTKDLKGRRPV 114
            |:|..||: .|.||:...|.|.| .|..:..:             |||||.||||...|....|:
Mouse    76 PEPPLPWN-GIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPL 139

  Fly   115 --IVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVL 177
              ::...|||.::....|.| .|.|.......|||.|.||||.|||.:||:..|.||.||.||:.
Mouse   140 LPVMVWFPGGAFLAGSASTY-EGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIA 203

  Fly   178 ALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDL 242
            ||||:|::|:.||||||||||.|.|||::||:..|:||:::||||:.|..|...........:.|
Mouse   204 ALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPL 268

  Fly   243 QLAKRQAGLLKCPQESIGEMVECMR-----------RKPYLDYVSTYNGMFEFGW--NPVLNWRI 294
            ..||:.|.|..|...|...||||:|           ::......:::....|..|  :||:: .:
Mouse   269 TSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVD-GV 332

  Fly   295 VVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLR---NESIVNRYNRD--- 353
            |..:|          |.....||....|..:.|:...||.....|.::   |:.::|:.|.:
Mouse   333 VFPED----------PVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKIL 387

  Fly   354 WEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDA------LIGVSF 412
            |    |..:||.....|....:|    :|:.:::...::......:.:|:.||      |....:
Mouse   388 W----SFNVLLNITKEQVPVVAR----EYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAARY 444

  Fly   413 HRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRE---DP 474
            ||     ...:|:|.|.|::......:..|.|    |..|.|||.|||.    .|..|..   :.
Mouse   445 HR-----DAGSPVYLYEFKHHASSGIIIKPYN----GADHGDELSYLFG----SPFSKGSSAGEE 496

  Fly   475 ENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLE------IGNNLTAKSGGFF 533
            :.|.:::: :.|..||..|:|:.:...|     ||.:: :|:.||:      :|..|..|...|
Mouse   497 KEFSLQMM-KYWANFAHTGNPNGEKLPY-----WPRFD-KDEKYLQLDFDTRVGVKLKEKKMAF- 553

  Fly   534 LNRYQIWEDL 543
                  |..|
Mouse   554 ------WSQL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	168/582 (29%)
Ces4a	NP_666325.2	COesterase	33..554	CDD:395084	164/568 (29%)