Protein Alignment CG4757 and Ces2e

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_766347.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 564
• Identity: 160/564 - (28%)
• Similarity: 257/564 - (45%)
• Gaps: 97/564 - (17%)

  Fly    24 DTELGRVRGANL-TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQP 87
            :|..|:|||:.: .....:..|.|.||.:|:||:|.|||..|:..:||| .:.|.:....||.|.
Mouse    35 NTHTGQVRGSLVHVKDTDIAVHTFLGIPFAKPPVGPLRFAPPEAPEPWS-GVRDGTSHPNMCLQN 98

  Fly    88 WDNM---------------TDVSEDCLRLNVYT-------KDLKGRRPVIVFLHPGGFYVFSGQS 130
             ||:               ..:|||||.||:|.       .:|    ||:|::|.|...|  |.:
Mouse    99 -DNLMGSEDLKMMNLILPPISMSEDCLYLNIYVPAHAHEGSNL----PVMVWIHGGALTV--GMA 156

  Fly   131 KYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDS 195
            ....|.......|.|:|::.||||.|||.:||.:.|.||.|..|||.||||:||:|..|||:||.
Mouse   157 SMYDGSMLAATEDVVVVAIQYRLGVLGFFSTGDQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDR 221

  Fly   196 VTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIG 260
            ||:.|.|||..||:.|::||||:||||..|..|.....|.....:...:.:..|.|..|...:..
Mouse   222 VTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVHRIVANLSGCAAVNSE 286

  Fly   261 EMVECMRRKPYLDYVSTYNGMFEF--GWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVA 323
            .::.|:|.|...:.:: .|.:|:.  |         ||:.:|     |.:.|.:.....|||.|.
Mouse   287 TLMCCLRGKNEAEMLA-INKVFKIIPG---------VVDGEF-----LPKHPQELMASKDFHPVP 336

  Fly   324 LITGIT--EFEFLSGAFFD--LRNESIVNRYNRDWEHYASIALLLEQNSTQSR---AASRVFREK 381
            .|.||.  |:.::.....|  .:.|.|..:         ::..:|:..:.:..   ....:..|:
Mouse   337 SIIGINNDEYGWILPTIMDPAQKIEEITRK---------TLPAVLKSTALKMMLPPECGDLLMEE 392

  Fly   382 YMPESLDKLEYPKSLKG-MGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQ 445
            ||.::.|    |::|:. ..|:..|.:..:...:.......|.|:|.|.|::  |.:|.|: ...
Mouse   393 YMGDTED----PETLQAQFREMKGDFMFVIPALQVAHFQRSHAPVYFYEFQH--RPSFFKD-FRP 450

  Fly   446 QTIGPVHHDELIYLFHV---GLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLN 507
            ..:...|.||:..:|..   .:.:|..:.|:.   :...:.:.|..||:.|:|:::...|
Mouse   451 PYVKADHGDEIFLVFGYQFGNIKLPYTEEEEQ---LSRRIMKYWANFARHGNPNSEGLPY----- 507

  Fly   508 WPLYNAQDKGYLE------IGNNLTAKSGGFFLNRYQIWEDLFP 545
            ||:.: .|:.||:      :|..|.|:       |.|.|....|
Mouse   508 WPVMD-HDEQYLQLDIQPSVGRALKAR-------RLQFWTKTLP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	158/557 (28%)
Ces2e	NP_766347.1	COesterase	30..538	CDD:395084	158/557 (28%)