Protein Alignment CG4757 and Ces2b

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 588
• Identity: 168/588 - (28%)
• Similarity: 265/588 - (45%)
• Gaps: 113/588 - (19%)

  Fly     2 LMLFVVELLVLLA-----SSSVLSIEVDTELGRVRGANL---TSRLGVNFHAFRGIRYAEPPLGD 58
            ::||  .||:||.     .|...|...:|..|:|||:.:   .::.||  |.|.||.:|:||:|.
Mouse    12 VLLF--GLLLLLGHVQGQDSPEASPIRNTHTGQVRGSLVHVKDTKAGV--HTFLGIPFAKPPVGP 72

  Fly    59 LRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDV---------SEDCLRLNVYT-------KD 107
            |||..|:..:||| .:.|.:....||.|....|.::         |||||.||:||       .:
Mouse    73 LRFAPPEAPEPWS-GVRDGTAHPAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSN 136

  Fly   108 LKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGL 172
            |    ||:|::|.||  :.:|.:....|.......|.|:|::.||||.|||.:||.:.|.||.|.
Mouse   137 L----PVMVWIHGGG--LVAGMASMYDGSLLAAIEDLVVVTIQYRLGVLGFFSTGDQHARGNWGF 195

  Fly   173 KDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKY 237
            .|||.|||||||:|..|||.||.||:.|.|||..||:.|::||||:||||..|..|.....|...
Mouse   196 LDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLI 260

  Fly   238 KDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNW-RIVVEKDFG 301
            .|....::...|.|..|.......:|.|:|.|...:.::.         |.::.. ..||:.:|
Mouse   261 TDTSEMVSTTVAKLSGCEAMDSEALVRCLRGKSEAEILAI---------NKLVQMIPAVVDGEF- 315

  Fly   302 QERYLIESPFKTARRGDFHKVALITGITEFEF------LSGAFFDLRNESIVNRYNRDWEHYASI 360
                ....|.:.....|||.|..|.|:...||      :.|:...::.   :.|.|        :
Mouse   316 ----FPRHPKELLASEDFHPVPSIIGVNNDEFGWTIPVVMGSAQTIKE---ITREN--------L 365

  Fly   361 ALLLEQNSTQ---SRAASRVFREKYMPESLD----KLEYPKSLKGMGELLSDALIGVSFHRFLQL 418
            ..:|:..:.|   ....|.:..|:||.::.|    ::::.       |::.|.:..:...:....
Mouse   366 QAVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQFT-------EMMEDFMFVIPALQVAYF 423

  Fly   419 MSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVH----H-DELIYLFHVGLLIPLLKREDPENFM 478
            ...|..:|.|.|::  :...||:      :.|.|    | ||:.::|........|...:.|..:
Mouse   424 QRSHASVYFYEFQH--QIASLKD------VRPTHVKADHADEIPFVFGYFFWDMKLDFTEGEKLL 480

  Fly   479 IELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLE------IGNNLTAKSGGFFLNRY 537
            ...:.:.|..||:.|:|:::...|     ||:.: .|:.||:      :|..|.::       |.
Mouse   481 SRRMMKYWANFARHGNPNSEGLPY-----WPVMD-HDEQYLQLDTQPAVGRALKSR-------RL 532

  Fly   538 QIW 540
            |.|
Mouse   533 QFW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	160/563 (28%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	160/564 (28%)