Protein Alignment CG4757 and Ces1f

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 586
• Identity: 173/586 - (29%)
• Similarity: 261/586 - (44%)
• Gaps: 130/586 - (22%)

  Fly     4 LFVVEL--LVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFR-------GIRYAEPPLGDL 59
            ||:|.|  .|:..:.|...: |||..|:|.|.:      ||...|.       ||.:|:||||.|
Mouse     6 LFLVSLATCVICGNPSSPPV-VDTAHGKVLGKH------VNVEGFSQPVAVFLGIPFAKPPLGSL 63

  Fly    60 RFVNPQPVKPWSPKIFDASEDGPMCPQPW-------DNMT--------DVSEDCLRLNVYTK--- 106
            ||..|||.:||| .:.:|:...|||.|..       |.:|        :.|||||.||:||.
Mouse    64 RFAPPQPAEPWS-SVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADF 127

  Fly   107 DLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDR------DCVLVSLNYRLGSLGFLATGSKE 165
            ....|.||:|::|.||.        .|.|...|..|      :.|:|::.|||...||.:||.:.
Mouse   128 SKNSRLPVMVWIHGGGL--------KLGGASSFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEH 184

  Fly   166 APGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAA 230
            :.||.|..|||.||.|:|.:|..|||||.|||:.|.|||..||::.:|||:|:.||||.|..|..
Mouse   185 SRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGV 249

  Fly   231 PYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLN-WRI 294
            .:.|..:..:...:.::.|....|...:...:|.|||:|       |...:.|....  || :::
Mouse   250 AFIPGMFTKDVRPITEQIAVTAGCKTTTSAVIVHCMRQK-------TEEELLEIMHK--LNLYKL 305

  Fly   295 VVEKDFGQERYLIES----------PFKTARRGDFHKVALITGITEFE----------FLSGAFF 339
            .::.|.......:.|          |.:.....:|:.|..|.||.:.|          ||..
Mouse   306 SLQGDTKNSDQFVTSVLDGVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMTGFLPA--- 367

  Fly   340 DLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFR---EKYMPESLDKLEYPKSLK-GMG 400
            |::           .:...:|| ||||.::.:.....:..   |||...|.|    |..:: |:.
Mouse   368 DVK-----------LDKKKAIA-LLEQFASMTGIPEDIIPVAVEKYTKGSDD----PDQIREGVL 416

  Fly   401 ELLSDALIGVSF------HRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYL 459
            :.:.|...||..      ||     ....|.|.|.::|   |....:|...:.:...|.|::..:
Mouse   417 DAMGDVAFGVPSVIVSRGHR-----DTGAPTYMYEYQY---YPSFSSPQRPKNVVGDHADDVYSV 473

  Fly   460 FHVGLLIPLLKR--EDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEI 521
            |..    |:|:.  .:.|..:.:::.:.|..||:.|:|:.      ||| :||.|: |.:|||.|
Mouse   474 FGA----PILREGASEEEINLSKMVMKFWANFARNGNPNG------KGLPHWPKYD-QKEGYLHI 527

  Fly   522 G 522
            |
Mouse   528 G 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	167/568 (29%)
Ces1f	NP_659179.1	COesterase	22..545	CDD:395084	167/570 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561