Protein Alignment CG4757 and Aadacl3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001078972.1
• Gene: Aadacl3 / 230883
• MGIID: 2685281
• Length: 408
• Species: Mus musculus
• Alignment Length: 252
• Identity: 53/252 - (21%)
• Similarity: 87/252 - (34%)
• Gaps: 74/252 - (29%)

  Fly     4 LFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNF---HAFRGIRYAEPPLGDLRFVNPQ 65
            :.|:.|.:|:.|.:|.|:           .:|...:|.:|   |...||.:
Mouse     1 MVVLALTLLVGSVAVFSL-----------GSLLWVVGKHFWTEHIPEGITH-------------- 40

  Fly    66 PVKPWSPKIFDA-----------SEDGPMC--PQPWDNMTDVSEDCLRLNVYTKDL--------- 108
               ||..:|...           .|...:|  ||....:.|:.......:|..|||
Mouse    41 ---PWRLRILSCLFHLTMTWGMIFEKLGLCYAPQFASFLHDLKPLKRDPDVVVKDLHFGTIPVKL 102

  Fly   109 -KGRRPV------IVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEA 166
             |.::|.      |:|.|.||..:.|.::..........:.|.|:||:.||...: :.....|:
Mouse   103 YKPKKPSSIPRLGIIFFHGGGTIIGSLRTHNSICLRLSKECDSVVVSVGYRKSPM-YKYPVMKD- 165

  Fly   167 PGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHR 223
                   |.|:|.....:.:..:|.||..|...|.|.|..:..:     .|:.|.||
Mouse   166 -------DCVVATTHFLESLDVYGVDPARVVTCGDSVGGTAATV-----TSQMLVHR 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	48/236 (20%)
Aadacl3	NP_001078972.1	Abhydrolase_3	116..379	CDD:400284	27/109 (25%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	120..122		1/1 (100%)