Protein Alignment CG4757 and cest-28

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 149/526 - (28%)
• Similarity: 228/526 - (43%)
• Gaps: 101/526 - (19%)

  Fly    20 SIEVDTELGRVRGANLTSRLG-VNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPM 83
            |.:::...|.::|.  ..|:| .....:.||.:|:|.   :||..|:|...|. ::.|.::.||.
 Worm    14 SEKLNATCGPIQGN--VYRIGDKTVDGYLGIPFAKPL---VRFKKPEPAGTWE-EVRDCTKYGPR 72

  Fly    84 CPQ--PWDNMTDVSED-------CLRLNVYTK--DLKG---RRPVIVFLHPGGFYVFSGQSKY-- 132
            |||  |:....:..:|       ||.|||::|  |.|.   .|||:|::|.|| |..|....|
 Worm    73 CPQSGPFAEAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTRPVMVYIHGGG-YECSASRDYCD 136

  Fly   133 --LAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDS 195
              :||....  :|.|:|:||||:|.|||..||....|||..|.|..|.|.|||:||:.|||||.:
 Worm   137 YSVAGTLPL--KDVVVVTLNYRVGILGFFTTGDTVCPGNFALWDLTLGLNWIQKHIESFGGDPGN 199

  Fly   196 VTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA---APYGPVKYKDNDLQLAKRQAGLLKCPQE 257
            :|:.|.|||:..|.|..|||.||.||:|.|.||.   ..|. |:..::..::....|..|.....
 Worm   200 ITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYA-VRTANSQAKVCYEFARHLGYDGT 263

  Fly   258 SIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDF---GQERYLIESPFKTARRGDF 319
            :...:...|:.|| |:.:...|| |:...:.:|.|...::.||   ..:...|.:|.|....|..
 Worm   264 NSQTLFNWMKSKP-LEEIEKMNG-FQVPASGILAWTPNLDDDFFPKSLDELRIGAPKKDIMMGFA 326

  Fly   320 HKVALITGITEFEFL----------------------SGAFFDLRNESIVNRYNRDWEHYASIAL 362
            ....|.     ||||                      :|..|:.....|:..|:|:.|.
 Worm   327 EHEGLF-----FEFLIKDPTPPLEALKLYVNEYYKKDTGDHFEATRNKIIEFYSRNVED------ 380

  Fly   363 LLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALI--GVSFHRFLQLMSPHTPI 425
             .::.||:.|                          :.:.:.|||.  || |......:.....:
 Worm   381 -TDEKSTKER--------------------------LIDFVGDALFTAGV-FDNAKNCLKHGNNV 417

  Fly   426 YTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFA 490
            :.|:|.|.....|....:....:.|.|..:|.|:...||.......|: |:.|||.:|.::..||
 Worm   418 WLYIFDYCNPSGFGNQEEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEE-EHKMIEKMTTIYSNFA 481

  Fly   491 QKGDPH 496
            :.|:|:
 Worm   482 KYGNPN 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	149/526 (28%)
		Aes	40..>204	CDD:223730	71/182 (39%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	148/523 (28%)
		Aes	<112..>222	CDD:223730	52/112 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820