Protein Alignment CG4757 and cest-8

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 147/589 - (24%)
• Similarity: 241/589 - (40%)
• Gaps: 155/589 - (26%)

  Fly     2 LMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQP 66
            :::.::.|..||.....|.| ::|..|::||....|....:...|:.:.:|:||:|:|||..||.
 Worm     1 MLVSILLLCSLLYEFQTLKI-INTSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLRFAPPQK 64

  Fly    67 VKPWSPKIFDASEDGPMCPQPWDNMT-----DVSEDCLRLNVYT--KDLKGRRPVIVFLHPGGFY 124
            :..|. .|.|||.....|   ..|.|     .|:||||.:|::|  |.||.:..|||:.| ||.|
 Worm    65 LDHWD-GILDASVYSAAC---MSNSTLTTQSYVNEDCLYINIFTSEKCLKSKCSVIVYFH-GGAY 124

  Fly   125 VFSGQSKYLAGPEHFMDR----DCVLVSLNYRLGSLGFLATG-SKEAPGNAGLKDQVLALRWIQQ 184
              :.:|..:......:||    |.:.|....|||..|.|..| :.....|..:.|.:|||.::..
 Worm   125 --NTESATMFSDRFILDRYVHEDVIFVIPAVRLGVFGQLYFGPNAYLTENLFMFDAILALDFVHN 187

  Fly   185 HIQRFGGDPDSVTLLGYSAGSISV-AL---HMLSPMSRGLFHRGICMSAAPYGPVKYK----DND 241
            .|..|||||:.||::|:|:|...| ||   .|:.|..: ||.:.|.:|:.  |...:.    ||.
 Worm   188 EISNFGGDPEKVTIMGHSSGGTLVEALGFSSMVDPELK-LFQQMIMLSST--GMFGFDDLVIDNS 249

  Fly   242 LQLAKRQAGLLKCPQE-----SIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFG 301
            ..:.:: .|.....:|     ::.|.::|||   ::|                           |
 Worm   250 FTIVEK-LGCFNGTKEERNTVNVAETLDCMR---HID---------------------------G 283

  Fly   302 QERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQ 366
            .|...::           .|:.|:..::....|.||.|.|.|.:|.:               |::
 Worm   284 YEILRVQ-----------QKMELMDQLSFKYLLRGAPFMLLNGNIAD---------------LKK 322

  Fly   367 NSTQSRAASRVF----------REKYMPESLDKLEYP-----------KSLKGMGELLS--DALI 408
            |::...|   :|          .|||:..::..|:|.           :.:|.|..:::  .|.|
 Worm   323 NTSPRNA---IFGTTEHEFFDVTEKYLYITVTFLDYENPVAVARNYDGRLMKNMETMITGDSAAI 384

  Fly   409 GVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVH--HDELIYLFHVGLLIPLLKR 471
            .||.......|: :.....:||..:..|: :...|.|..||. |  |:..|   .:.:|
 Worm   385 FVSTATCAAAMA-NAGADVFLFETRQSYS-VHVSDMQYFIGN-HCAHNRTI---DIDIL------ 437

  Fly   472 EDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKG---YLEIGNNLTAKSGGFF 533
               ::|..:|||    .|.:.|.|.            |.::..|.|   |||:..:..|:||...
 Worm   438 ---DSFYSKLLT----NFTKHGKPS------------PGWDPVDPGRMNYLELKVDSKARSGPVM 483

  Fly   534 LNRY 537
            |..|
 Worm   484 LEGY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	144/576 (25%)
		Aes	40..>204	CDD:223730	61/175 (35%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	143/571 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157136
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740