Protein Alignment CG4757 and cest-30

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 165/610 - (27%)
• Similarity: 255/610 - (41%)
• Gaps: 137/610 - (22%)

  Fly     2 LMLFVVE--LLVLLA---SSSVLSIEVDTELGRVRGANLTSRLGVNF-HAFRGIRYAEPPLGDLR 60
            |:|.:||  .||.|.   :|.:|    :...|.:||.....:.|... ..:.||.:|:.|:|.|:
 Worm    12 LLLSIVEGGFLVNLTPEKNSQIL----NAPCGPIRGNIYKHKNGTKIVDGYLGIPFAKAPVGALK 72

  Fly    61 FVNPQPVKPWS-PKIFDASEDGPMCPQP--WDNMTDVS------EDCLRLNVYTKDLKGRR---- 112
            |..|...:.|: |:  |..|.||.|||.  :..:|..|      |:||.|||:....|...
 Worm    73 FKKPVAAEKWTEPR--DCYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKG 135

  Fly   113 -PVIVFLHPGGFYVFSGQSKYLAGPEHFMD----------RDCVLVSLNYRLGSLGFLATGSKEA 166
             ||:|:::.||:.:         |...:||          :|.::|::|||||.||||......|
 Worm   136 LPVLVYIYGGGYEI---------GFTSYMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIA 191

  Fly   167 PGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAP 231
            .||.||.||.|||:|:|.:|..|||:|:||||.|.|||:.|.....|||.|..||.|.|.||...
 Worm   192 NGNYGLWDQTLALQWVQDNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTA 256

  Fly   232 Y--GPVKYKDNDLQLAKRQA---GLLKCPQESIGE--MVECMRR-KPYLDYVSTYNGMFEFGWNP 288
            :  ..::.||.::.:.|..|   |......:|:.:  |.:.:.: |....:.||..|...|
 Worm   257 FCNFAIRPKDVEVGVCKEFAQFQGYTGTDSQSLFDWYMAQNVSKFKEVAGFQSTAAGAVPF---- 317

  Fly   289 VLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNR- 352
            :.|:    :.||      ...||...||....|.||||.:| .|.:....|   |....|.||.
 Worm   318 IPNF----DGDF------FPKPFDILRREAPKKDALITVVT-MESVGMIIF---NPLFANAYNNF 368

  Fly   353 -----------DWEHYASIA------LLLEQNSTQSRAASRVFREKYMPESL---DKLEYPKSLK 397
                       ..::||.:.      .|.:.|::.....:|...: |:.:|:   ..|:..||..
 Worm   369 EGFINETYGPDVTDYYADVKKKLTGFYLKDVNASDKATVNRRVVD-YVSDSVFNSGTLDAVKSYV 432

  Fly   398 GMGELLSDALIGVSFHRF-------LQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDE 455
            ..|   :...:| ||:.|       ::||.|        |:...                 |..:
 Worm   433 KYG---NKVYLG-SFNYFNDATKDMVELMQP--------FKEAS-----------------HSSD 468

  Fly   456 LIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLN-WPLYN-AQDKGY 518
            ..|.|..|::..... .|.|..::::...:...|.:.|||:.|:     |.. |..|. .:...|
 Worm   469 FKYYFGSGVMANFTP-TDEEMEVMDMSGTLMANFVKYGDPNGKS-----GTKPWKPYTILKPNMY 527

  Fly   519 LEIGNNLTAKSGGFFLNRYQIWEDL 543
            .:|.......|..|...|.:|::|:
 Worm   528 YKIDYPTCEMSDNFQNGRLRIYDDI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	154/582 (26%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	156/585 (27%)