Protein Alignment CG4757 and ace-1

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 162/573 - (28%)
• Similarity: 266/573 - (46%)
• Gaps: 89/573 - (15%)

  Fly     9 LLVLLASSSVLSIE-VDTELGR-VRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWS 71
            |..:...|::|::: :....|. :.|..:.|:.|.....|:||.:||||:|:|||..|:|.:||.
 Worm     6 LFFIFLPSTILAVDLIHLHDGSPLFGEEVLSQTGKPLTRFQGIPFAEPPVGNLRFKKPKPKQPWR 70

  Fly    72 PKIFDASEDGPMCPQP-------------WDNMTDVSEDCLRLNVYTK---DLKGRRPVIVFLHP 120
            ..: :|:.....|.|.             |:..|.:|||||.||||..   |...:..|:|:::.
 Worm    71 IPL-NATTPPNSCIQSEDTYFGDFYGSTMWNANTKLSEDCLYLNVYVPGKVDPNKKLAVMVWVYG 134

  Fly   121 GGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQH 185
            |||:..:.......|....::.:.:||::|||:...|||.....|||||.|:.||:||::|:.::
 Worm   135 GGFWSGTATLDVYDGRILTVEENVILVAMNYRVSIFGFLYMNRPEAPGNMGMWDQLLAMKWVHKN 199

  Fly   186 IQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQA- 249
            |..||||...:||.|.|||:.||::|||||.|...|||.|..|.:...|...:..|:.||:...
 Worm   200 IDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDVALARAVIL 264

  Fly   250 -GLLKCPQESI-----GEMVECMRRKPYLDYVSTYNGMFEFGWNPV-----LNWRIVVEKDFGQE 303
             ..:||...|:     ..:::|.:|       :..:.:.|..|.||     ..|..||:.||
 Worm   265 YNAMKCGNMSLINPDYDRILDCFQR-------ADADALRENEWAPVREFGDFPWVPVVDGDF--- 319

  Fly   304 RYLIESPFKTARRGDFHKVALITGITEFE---FLS--------GAFFDLRNESIVNRYNRDWEHY 357
              |:|:...:.::|:|.|..|:.|....|   ||:        .|.|..:.:.|.:|  :.|  .
 Worm   320 --LLENAQTSLKQGNFKKTQLLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDR--QLW--I 378

  Fly   358 ASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKS-LKGMGELLSDALIGVSFHRFLQLMSP 421
            ..:..||.:...:.:........:|.|:.|...  |:. :..|.::|.|.....|.:   ::...
 Worm   379 KGVKDLLPRQILKCQLTLAAVLHEYEPQDLPVT--PRDWINAMDKMLGDYHFTCSVN---EMALA 438

  Fly   422 HT----PIYTYLFRYKGRYTFLKNPDNQQT----IGPVHHDELIYLFHVGLLIPLLKREDPENFM 478
            ||    ..|.|.|.::.         :|||    :|.:|..|:.::|...|........|.|..:
 Worm   439 HTKHGGDTYYYYFTHRA---------SQQTWPEWMGVLHGYEINFIFGEPLNQKRFNYTDEEREL 494

  Fly   479 IELLTRMWIEFAQKGDPHNKNDE--YLKGLNWPLYNAQDKGYLEIGNNLTAKS 529
            .....|.|..||:.||| |||::  :.:.: ||.||:....|:    |:|.:|
 Worm   495 SNRFMRYWANFAKTGDP-NKNEDGSFTQDV-WPKYNSVSMEYM----NMTVES 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	159/562 (28%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	159/559 (28%)