Protein Alignment CG4757 and cest-19

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 160/579 - (27%)
• Similarity: 263/579 - (45%)
• Gaps: 103/579 - (17%)

  Fly    13 LASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDA 77
            :::..:...|:....|.:||..|.:. |.::..|:||.:|.||:|.|||..|:....|. .:.:|
 Worm    18 ISTRHISPFELRVNSGAIRGERLLTD-GQDYSVFKGIPFAMPPVGYLRFQMPKEPAKWR-GVMNA 80

  Fly    78 SEDGPMCPQPWDN---------MTDVSEDCLRLNV-------YTKDLKGRRPVIVFLHPGGFYVF 126
            ::...||.|..|.         :..||||||.|||       ||.|   ..|||||:|.|.|...
 Worm    81 TQYSAMCMQNIDENDAGEPERYVAHVSEDCLYLNVFSPTPYQYTND---TYPVIVFIHGGRFQTG 142

  Fly   127 SG----QSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQ 187
            ||    |...|:   :|:.|..|.|:.|||||.|||.:||....|||.||.||:.||:|::.:.:
 Worm   143 SGSDIPQRAILS---NFVSRKIVFVTFNYRLGPLGFASTGDSVLPGNIGLWDQIWALKWVKANAE 204

  Fly   188 RFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLL 252
            .|||||.::.|:|:..|:.|.:|..|||.:.|||.:.:.||.:...|...::..:..........
 Worm   205 VFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSALQPGVVRNTQVNATWNMNDRF 269

  Fly   253 KCPQESIGEMVECMRRK--------------PYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQE 303
            .|...:..|:::|.|::              .|.::|            |:::         |..
 Worm   270 GCRAFNSSELLDCARKRSKEEIFQYKRLHFDDYEEFV------------PIID---------GVG 313

  Fly   304 RYLIESPFK-TARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIA--LLLE 365
            ..|.|.|.: |..|   .|..::.|.|:.|  |.....|.||..:|..:..||:..::|  |.|.
 Worm   314 GILPEPPEQLTLHR---RKTPIVIGTTKDE--SSLRILLLNEKDLNFSSITWENGETLADNLTLG 373

  Fly   366 QNSTQS-RAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYL 429
            ....|: |..|:..:.:|:...:|. .:|:|      :|.::|:.:..|.:..  :|.:.:.||.
 Worm   374 FKQFQNHRLISQGCKSEYVWTQVDP-SFPES------VLFNSLLKMYSHFWYD--APASQLATYY 429

  Fly   430 FRYK---GRYTFLKNPDNQQTIGPVHH--DELIYLFHVGLLIP--LLKREDP----ENFMIELLT 483
            .::.   ..|:|....:|...|....|  |:|    |:..:.|  |.||:|.    :..::|:.:
 Worm   430 LKHDLPVYLYSFDHISENFYDIDRAFHGVDKL----HIFNVTPRFLNKRKDMNWQLDQRVVEIFS 490

  Fly   484 RMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAK-----SGGFFLNRY 537
            .:...||..|.|.::||.:  ..||....|::..||.|.::.:.:     .|..|.|.|
 Worm   491 ELVANFALYGTPTHENDGF--SFNWTSTTAKELSYLSITDSPSMQVGYRWQGHVFWNWY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	160/577 (28%)
		Aes	40..>204	CDD:223730	73/183 (40%)
cest-19	NP_509187.4	Abhydrolase	27..544	CDD:389770	157/565 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910