Protein Alignment CG4757 and glit-1

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 604
• Identity: 153/604 - (25%)
• Similarity: 235/604 - (38%)
• Gaps: 160/604 - (26%)

  Fly    35 LTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPV------KPWSPKIFDAS-------EDGPMCPQ 86
            |..:..:....|.|:.|||||....||..||.:      :|:....:.||       ...|....
 Worm    98 LKPKNNITVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSPSPFVDH 162

  Fly    87 PWDNMTDVSEDCLRLNVYTKDLKGRR----PVIVFLHPGGFYVFSGQSKYLAGPEH-FMDRDCVL 146
            |:..|.|  ||||.||:::.|:....    |||||.|.|.|...|...    .|.| ...|..|:
 Worm   163 PYPFMVD--EDCLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSANE----WPAHGLASRGMVV 221

  Fly   147 VSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALH 211
            |::|||||:.||::.|..|. ||.||:||.|||.:::.:|..|||||.:||::|:.||:.|:..|
 Worm   222 VTVNYRLGAFGFMSMGDSET-GNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFH 285

  Fly   212 MLSPMSRGLFHRGICMSAAPYGPVKYK----------DNDLQLAKRQAGLLKCPQ---------- 256
            |.||.||.||.....||.|   .|.|.          :|.::|. |.||   |.|
 Worm   286 MQSPYSRHLFRSAATMSGA---EVSYHSYIGKTALAFNNTMKLG-RYAG---CTQAVAQHRWDCI 343

  Fly   257 --ESIGEMVECMRRKP-----YLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESP---- 310
              .|.|::::..|..|     || ::.|.:|.:..| ||:  |.: |....|:...:...|
 Worm   344 LTRSTGDIIDATRNIPIEYNRYL-FMPTVDGKYLPG-NPL--WTL-VNAPSGETSIMSPVPMLIG 403

  Fly   311 ----------FKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVN-------RYNRDWEHYA 358
                      .:..|.|:|.:                |.|:.:|.:.:       |:|......|
 Worm   404 MNAQDGSEVVLEDRRLGEFSQ----------------FNDVDHEYLKSYSLEYCYRHNYSMNREA 452

  Fly   359 SI-ALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSP- 421
            :. |:|.:......|||:...:|.::                 :..:||.    :...:||.|.
 Worm   453 TADAILSKYTFWPDRAAAWAIKENFI-----------------QFATDAY----YTAPMQLSSHL 496

  Fly   422 HTPIYTYLFRYKGRYTFLKNPDN----QQTIGPVHHDELIYLFHVGLLIPLLKRE---------- 472
            |:...:.:|:|...|.|.:...|    ...:|.....:|..:|.    .|.|..|
 Worm   497 HSSSGSRVFQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFG----YPFLPDELRPIGLRGIN 557

  Fly   473 --DPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTA----KSGG 531
              |.:.......:.:...|:...:|:.:.|.     :|..|..:...|:..  |.|.    |..|
 Worm   558 FTDTDRNASRTFSNIIRRFSYHQNPNFQFDG-----SWAAYEPRRHWYINF--NYTHEEDWKIPG 615

  Fly   532 FFLN--RYQ---IWEDLFP 545
            ....  |||   .|.:..|
 Worm   616 TLARDYRYQDVAFWNEYIP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	151/597 (25%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	151/597 (25%)