Protein Alignment CG4757 and cest-26

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 166/579 - (28%)
• Similarity: 257/579 - (44%)
• Gaps: 96/579 - (16%)

  Fly    20 SIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMC 84
            |.:|.|..|.|.|..:..........|.||.:|:.|:|||||.||:..:.|. .:......||..
 Worm    41 SKQVRTRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWD-GVKKCVRFGPRA 104

  Fly    85 PQP---WDNMT---DVSEDCLRLNVYTKDLK------GRRPVIVFLHPGGFYVFS-------GQS 130
            ||.   |:..|   ..|||||.|||::...|      |..||:|::|.|||.:.|       |.:
 Worm   105 PQADFFWERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEGIA 169

  Fly   131 KYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDS 195
            |||.  .|    ..|:|::.||||.|||.:||.:..|||.||.|..:||:|::.::..|||||..
 Worm   170 KYLC--RH----GVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRK 228

  Fly   196 VTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYK---DNDLQLAKRQAGLLKCPQE 257
            ||:.|.|||.:||.|..|||.||.|||:.:.|  |..|..::.   .|.|..|.|:....||..|
 Worm   229 VTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPM--AGNGECEWSTVGKNRLVNACREFAYRKCWDE 291

  Fly   258 SIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRG-DFHK 321
                       |...| .:....|.||       .|...|::|  |:.|:      .|:| |..|
 Worm   292 -----------KQARD-ENASESMLEF-------LRTRKEREF--EKRLL------TRKGVDVSK 329

  Fly   322 VAL----ITGITEFEFLSGAFFDLRNES-----IVNRYNRDWEHYASIA---------------L 362
            :.|    :.|....:||..:..:||.|:     :|.....:...:||:.               |
 Worm   330 IGLDLAPVIGSKPSDFLPKSIEELRKEAPKKNIMVGTCEHEGLLFASLGPSNFDEKGIDKLLALL 394

  Fly   363 LLEQNSTQSRAASRVFREKYMPE-SLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSP-HTPI 425
            :.|:|.....|.....::.|:.: |.|:.:...:.:|..:|.||..:....:.:.:.|:. ...:
 Worm   395 ITEENHEDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEKMTKLGNKV 459

  Fly   426 YTYLFRYKGRYTF----LKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMW 486
            :.|.|.|....:|    |:.|....|    |..||.|:|.|.::.. .:..:.:..|::|:|:||
 Worm   460 FMYSFDYCNPRSFGILSLRAPFRAAT----HCTELAYIFGVSIVFN-YRYNESDRAMLDLMTKMW 519

  Fly   487 IEFAQKGDPHNK-NDEYLKGLNW-PLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDL 543
            ..||:.|:|:.: .|..:....| |....:...:|.|..........:..||.:.|:.:
 Worm   520 TNFAKYGNPNGQYEDSTVFDFKWEPTSKEEPTNFLAINEKKCEMQTVYQDNRAEFWKKI 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/574 (29%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	165/574 (29%)