Protein Alignment CG4757 and cest-17

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 158/545 - (28%)
• Similarity: 241/545 - (44%)
• Gaps: 49/545 - (8%)

  Fly    22 EVDTELGRVRGANLTSRL-GVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMC- 84
            :|.|..|.:.|....|.: |..:|.|.||||..||....||..|:||:.|.....||:.....|
 Worm    23 KVTTPYGPIVGFEHKSTVTGSKYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCI 87

  Fly    85 ---PQPWDNMTDVSEDCLRLNVYT-KDLKGRR-PVIVFLHPGGFYVFSGQSK--YLAGPEHFMDR 142
               ....:...:.|||||.||:.| .|.|.:: ||:||:|.|||. |...|.  |....::|:.:
 Worm    88 PSLRSELEEQVNYSEDCLFLNIVTPPDAKEKKLPVLVFIHGGGFQ-FGDTSMIGYQKAADNFVSK 151

  Fly   143 DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSIS 207
            |.:.||:.||||.|||..||..|.|||.||.||.|||:::.:.:..||||||.:||.|:|||:.|
 Worm   152 DIIFVSIQYRLGPLGFFTTGDSEIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGAAS 216

  Fly   208 VALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYL 272
            |:..:.||.|..||.:.|.:|.:.:.......|.:..:::.|....||||...|:.:|:..:...
 Worm   217 VSALLYSPHSDHLFSQAIQLSGSIFSESNLDRNVVDDSRKLAKAAGCPQEDSKELRDCIEIRTVD 281

  Fly   273 DYVSTYNGMFEFGWNP-VLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSG 336
            :.:.....:.|....| ...:....:|||..  |.||   |.:|:..  |...:.|:...|....
 Worm   282 ELLDAMESIGELLPGPRTKKFHPYFDKDFFP--YDIE---KMSRKAP--KKRTMQGLVSLESGLS 339

  Fly   337 AFFDLRNESIVNRYNRDWEHYASIALL--------LEQN-STQSRAASRVFREKYM--PESLDKL 390
            ..:.::...::......|..|:...|:        :||. .|.|...|.:..|.|:  |.:.:..
 Worm   340 VLYPVKLAKLLGVPKESWSTYSKDNLVDFIRSQVAVEQEFGTASARFSGLVEEFYLSGPMTGNSS 404

  Fly   391 EYPKSLKGMGELLSDALIGVSFHRFLQLMSPH-TPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHD 454
            .|   |.....||||....:.....::|...| ...|.|:..|....|  |:| .....||.|..
 Worm   405 FY---LNAFANLLSDLQYNIPTLHEVELKLQHGWDTYLYIIDYDSETT--KDP-THPIKGPFHAS 463

  Fly   455 ELIYLFHVGLL--IPLLKREDP-ENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDK 516
            ||.|||:...:  ||...::.. ||:.:..:    :.|...|.|..      |.|.||..:....
 Worm   464 ELRYLFNFNGMDTIPFNDKDKKFENYFVNAI----VNFINTGTPST------KALLWPAVSKSQP 518

  Fly   517 GYLEIGNNLTAKSGGFFLNRYQIWE 541
            ....:.|:..:....|....|::|:
 Worm   519 FANLLLNDKPSVQTSFRQEAYELWQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	157/542 (29%)
		Aes	40..>204	CDD:223730	73/171 (43%)
cest-17	NP_505114.1	COesterase	20..542	CDD:278561	157/542 (29%)
		Aes	<109..>225	CDD:223730	53/116 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920