Protein Alignment CG4757 and cest-34

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 607
• Identity: 158/607 - (26%)
• Similarity: 245/607 - (40%)
• Gaps: 161/607 - (26%)

  Fly    19 LSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPM 83
            |...::|..|.|.| ||........|.:.|:.||:||.|::||..|.|...|: :..|.::.||.
 Worm    13 LGTVLNTSCGPVLG-NLYRHGDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWT-ETRDCTKYGPR 75

  Fly    84 CPQPWDNM-------TDVSEDC--LRLNVY-----TKDLKGRRPVIVFLHPGGFYVFSGQSKYLA 134
            ||.....:       .|..::.  |.:||:     :.:.|..|||:|::|.|||.:.|.:
 Worm    76 CPPSGQGLEKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSSR----- 135

  Fly   135 GPEHFMD---------RDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFG 190
               .|.|         :|.:||::|||||.|||..||.:..|||.||.||.|||:|:|:||..||
 Worm   136 ---EFCDYSISSTLPMKDVILVTMNYRLGILGFFTTGDEVCPGNFGLWDQTLALQWVQKHIASFG 197

  Fly   191 GDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCP 255
            |||::|||.|.|||...|.|..|||.||.||.:.:.||.:     ...:..::.|:.:|.:....
 Worm   198 GDPNNVTLFGQSAGGACVDLLTLSPHSRDLFQKVVPMSGS-----AMCEFAMRTAENEAHVFDDI 257

  Fly   256 QESIG-------EMVECMRRKP----------------YLDYVSTYNGMFEFGWNPVLNWRIVVE 297
            ...:|       |.:|.||..|                ::.....|:|.|
 Worm   258 LARLGFTGSGSKERLEFMRSLPCDKITGKTGYTYKQSGFMSLCPNYDGDF--------------- 307

  Fly   298 KDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRD--WEHYASI 360
                     ...|....|: |..|..|:|||            :.||.::..::|:  ::.|..:
 Worm   308 ---------FPKPLDELRK-DASKRILMTGI------------VGNEGLLFAFDRNTPYKDYTDL 350

  Fly   361 ALLLEQNSTQSRAASRVFREKYMPESLDKLE---------YPKS---------LKGMGELLSDAL 407
            ..|             ...|.|..:.:|.:|         |.|:         ::...|.:.|::
 Worm   351 LRL-------------KIEEDYKEDVVDDVEGIRKEIFEYYTKNISEGDEEAIMRKAAEFVGDSI 402

  Fly   408 IGVSFHRFLQLMSPH-TPIYTYLFRYKGRYTFLKNPDN-------QQTIGPVHHDELIYLFHVGL 464
            .........|..:.| ..::.|.|.|       .|||.       ...|.|.|..||.|||..|:
 Worm   403 FHTGVRATAQNAAEHGDEVWLYNFDY-------CNPDGFAPLKGYLPYIEPTHGMELRYLFGDGI 460

  Fly   465 LIPLLKREDPENFMIELLTRMWIEFAQKGDPH-------NKNDEYLKG----LNWPLYNAQDK-- 516
            :......|: |..|::..|.|:..||:.|:|:       .|.|....|    :::|....:|:
 Worm   461 ISKFEPTEE-ELKMLDKFTTMFANFAKYGNPNETGSSAWEKFDPARPGRHYRISYPNSGMEDEFS 524

  Fly   517 -GYLEIGNNLTAKSGGFFLNRY 537
             |..:....:..|:..|..|.|
 Worm   525 GGRWKFLEEIRKKNKSFQQNVY 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	157/606 (26%)
cest-34	NP_001360105.1	COesterase	15..517	CDD:395084	151/574 (26%)