Protein Alignment CG4757 and cest-33

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 162/543 - (29%)
• Similarity: 231/543 - (42%)
• Gaps: 119/543 - (21%)

  Fly    28 GRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWD--- 89
            |.||| |:.....|....:.||.||:||:|:|||..|..|..|: :|.|..:.||.|.|...
 Worm    22 GPVRG-NIYKHDDVIVDGYLGIPYAKPPVGELRFKKPVTVDVWT-EIKDCYKYGPACVQTGGFEQ 84

  Fly    90 -----NMTDVSEDCLRLNVYT-----KDLKGRRPVIVFLHPGGF----------YVFSGQSKYLA 134
                 ..|.....||.|||:|     .:.|..|||:|::|.||:          |..||....
 Worm    85 IAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGRPVMVYIHGGGYELCASSDFCAYSLSGTLPL-- 147

  Fly   135 GPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLL 199
                   :|.|:||:|||||..|||.||....|||.||.||.|||:|:|:||..|||||:.||:.
 Worm   148 -------KDVVVVSINYRLGVFGFLTTGDNVCPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVF 205

  Fly   200 GYSAGSISVALHMLSPMSRGLFHRGICMSAAPY--GPVKYKDNDLQL-----------AKRQAGL 251
            |.|||..|..|..|||.||.||.|.|.:|...:  ..::..:|..::           .:..:.|
 Worm   206 GQSAGGASTDLLSLSPHSRDLFQRFIPISGTAHCDFAIRASENQAKIFREFAEFHGFSGRDSSAL 270

  Fly   252 LKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARR 316
            .|..||...|.:..::     .|..:.:|...|..|        ::.||      ...|....|:
 Worm   271 FKWYQEQSPETLSNVK-----GYKKSISGFLTFIPN--------LDGDF------FPKPLDELRK 316

  Fly   317 GDFHKVALITGITEFEFL-----SGAF------FDLRNESIVNRYNRDWEHYASIALLLEQNSTQ 370
             :..|..::||:||:|.|     :.||      ..|..:.|   |.:|          :..|..:
 Worm   317 -EAPKKQMMTGVTEYEGLMLASMNPAFSPADVGLTLMPQGI---YGKD----------VVSNPDE 367

  Fly   371 SRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPH-TPIYTYLFRYKG 434
               ..::|.|||: |.:||.:.....|.:.|.|.|....|...:..:..:.| ..:|.|.|.|
 Worm   368 ---IQKIFYEKYV-EGVDKSDELAMRKKLCEALGDEFFNVGVIQAAKNAAKHGNEVYFYTFEY-- 426

  Fly   435 RYTFLKNPDN-------QQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQK 492
                 .|||:       ......||..||.||...|:.......|:....| |..|.::..||:.
 Worm   427 -----VNPDSFGMWDGMMPFKAAVHCTELRYLLGEGVYSKFEPTEEDRKVM-ETTTTLFSNFAKY 485

  Fly   493 GDPHNKN------DEYLKGLNWP 509
            |:|:.|.      ::|  .||.|
 Worm   486 GNPNGKGATAEIWEKY--SLNRP 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	162/543 (30%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	162/543 (30%)